Tenoren Plus 50 mg+25 mg (Tablet)
Unit Price: ৳ 3.02 (5 x 10: ৳ 151.00)
Strip Price: ৳ 30.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Atenolol chlorthalidone |
| Company | Aci limited |
Indications
- Treatment of hypertension
- Lowering blood pressure
- Reducing risk of cardiovascular events
- Effective in preventing strokes and myocardial infarctions
Pharmacology
- Atenolol and chlorthalidone combination
- No interference with bioavailability
- Convenient formulation for concomitant administration
- Beta1-selective (cardioselective) beta-adrenergic receptor blocking agent
- Reduction in heart rates and cardiac output
- Reduction of systolic and diastolic blood pressure
- Reflex orthostatic tachycardia reduction
- Monosulfonamyl diuretic with prolonged action
- Diuresis with increased excretion of sodium and chloride
Dosage & Administration
- Initial dose: Atenolol 50 mg and Chlorthalidone 25 mg once a day
- Optimal response adjustment with additional antihypertensive agent
- Dosage adjustment in cases of severe impairment of renal function
- Clinical studies did not include sufficient elderly subjects
Interaction
- Potentiation of other antihypertensive agents
- Concomitant use with catecholamine depletor may cause hypotension
- Additive effect with calcium channel blockers and Amiodarone
- Decreased hypotensive effects with prostaglandin synthase inhibiting drugs
- Increased risk of bradycardia with concomitant use of digitalis glycosides
Contraindications
- Hypersensitivity to the product or sulfonamide-derived drugs
- Sinus bradycardia
- Heart block greater than first degree
- Cardiogenic shock
- Overt cardiac failure
- Anuria
Side Effects
- Bradycardia
- Cold extremities
- Postural hypotension
- Leg pain
- Dizziness
- Vertigo
- Lightheadedness
- Tiredness
- Fatigue
- Lethargy
- Drowsiness
- Depression
- Dreaming
- Diarrhea
- Nausea
- Wheeziness
- Dyspnea
- Orthostatic hypotension
- Anorexia
- Gastric irritation
- Vomiting
- Cramping
- Constipation
- Pregnancy category D
Pregnancy & Lactation
- Caution when administered to a breastfeeding woman
Precautions & Warnings
- Aggravation of peripheral arterial circulatory disorders
- Periodic determination of serum electrolytes
- Detection of possible electrolyte imbalance
Overdose Effects
- No specific information available for human overdosage
- Symptomatic and supportive treatment
- Induced emesis or administration of activated charcoal
- Atenolol removal by hemodialysis
- Consideration for dehydration, electrolyte imbalance, and hypotension
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store in cool and dry place
- Protected from light