Intafenac K 50 mg (Tablet)

Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00

Medicine Details

Indications

  • Short-term treatment for post-traumatic pain
  • Management of post-operative pain and inflammation
  • Treatment of painful and/or inflammatory conditions in gynaecology
  • Relief from migraine attacks
  • Management of painful syndromes of the vertebral column
  • Use in non-articular rheumatism
  • Adjuvant therapy in painful inflammatory infections of the ear, nose, or throat

Pharmacology

  • Inhibition of cyclooxygenase (COX-1 and COX-2)
  • Potent inhibitor of prostaglandin synthesis
  • Sensitizes afferent nerves and potentiate the action of bradykinin
  • Mediator of inflammation

Dosage & Administration

  • Initial loading dose of 50 mg for adults
  • 25-50 mg to be taken every eight hours if necessary for adults
  • Initial loading dose of 50 mg for migraine, then further 25-50 mg after 2 hours if necessary
  • Maximum daily dose of 150 mg for migraine
  • Upto 75 mg daily in divided doses for children over 14 years of age

Interaction

  • Potential drug interactions with Lithium and Digoxin
  • Increased risk of hemorrhage with anticoagulant therapy
  • Reports of nephrotoxicity with concomitant use of Cyclosporin
  • Potential for serious toxicity when used with Methotrexate within 24 hours
  • Inhibition of diuretic activity when used with diuretics
  • Increased frequency of unwanted effects when co-administered with other NSAIDs and steroids

Contraindications

  • Contraindicated in patients with known hypersensitivity to Diclofenac
  • Not to be given to patients who have experienced asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs
  • Contraindicated for perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • Mild and transient side-effects
  • Occasional: epigastric pain, nausea, vomiting, diarrhea
  • Rare: gastrointestinal bleeding, peptic ulcer, bloody diarrhea

Pregnancy & Lactation

  • Not prescribed during pregnancy unless compelling reasons
  • Lowest effective dosage should be used during pregnancy
  • Not recommended during the last trimester of pregnancy
  • Small quantities may be detected in breast milk

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Keep below 30°C temperature
  • Away from light and moisture
  • Keep out of the reach of children

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