Nopain 25 mg (Tablet)

Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Diclofenac potassium
Company Drug international ltd
Also available as

Indications

  • Short-term treatment for post-traumatic pain and inflammation
  • Treatment for post-operative pain and swelling
  • Management of gynaecological pain and inflammation
  • Relief of migraine attacks
  • Management of painful syndromes of the vertebral column
  • Treatment for non-articular rheumatism
  • Adjuvant treatment for painful inflammatory infections of the ear, nose, or throat

Pharmacology

  • Inhibition of cyclooxygenase (COX-1 and COX-2)
  • Potent inhibitor of prostaglandin synthesis in vitro
  • Sensitization of afferent nerves by prostaglandins
  • Mediation of inflammation by prostaglandins

Dosage & Administration

  • Initial loading dose of 50 mg for adults
  • 25-50 mg every eight hours for adults
  • Additional dose of 25-50 mg for migraine after 2 hours
  • Maximum daily dose of 150 mg for migraine
  • Up to 75 mg daily in divided doses for children over 14 years

Interaction

  • Increased plasma concentrations of Lithium and Digoxin
  • Increased risk of haemorrhage with anticoagulant therapy
  • Reported cases of nephrotoxicity with Cyclosporin concomitantly
  • Serious toxicity when co-administered with Methotrexate
  • Inhibition of diuretic activity
  • Increased frequency of unwanted effects when co-administered with other NSAIDs and steroids

Contraindications

  • Known hypersensitivity to Diclofenac
  • History of asthma, urticaria, or allergic type reactions after taking aspirin or other NSAIDs
  • Severe, rarely fatal, anaphylactic-like reactions to NSAIDs
  • Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • Mild and transient side effects
  • Occasional: epigastric pain, gastrointestinal disorders, nausea, vomiting, diarrhea, abdominal cramps, dyspepsia, flatulence, anorexia
  • Rare: gastrointestinal bleeding, peptic ulcer, bloody diarrhea

Pregnancy & Lactation

  • Not recommended during pregnancy unless compelling reasons exist
  • Lowest effective dosage should be used during pregnancy
  • Not recommended during the last trimester of pregnancy
  • Small quantities may be detected in breast milk with no expected undesirable effects on the infant

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Keep below 30°C temperature
  • Store away from light and moisture
  • Keep out of the reach of children

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