Voligel 1% w/w (Gel)
50 gm tube: ৳ 97.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Surgery and Traumatology
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Obstetrics and Gynecology
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Otorhinolaryngology
- Dentistry
- Post-operative and post-traumatic pain
- Inflammation and swelling
- Urogenital tract
- Renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- Metabolized in the liver
- Undergoes first pass metabolism
Dosage & Administration
- Diclofenac FC Tablet for adults: 75-150 mg daily in 2 to 3 divided doses
- Diclofenac SR Tablet for adults: 1 tablet daily, preferably at meal times
- Diclofenac Dispersible Tablet for adults: 2-3 tablets daily
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository for adults: 50 mg suppository 2-3 times daily
- Diclofenac injection for adults: 1 ampoule daily
- Diclofenac Gel: 2-4 g applied to the skin 3-4 times daily
Interaction
- May increase plasma concentrations of lithium and digoxin
- Increased risk of haemorrhage with the combined use of diclofenac and anticoagulant therapy
- Can be given together with oral antidiabetic agents without influencing their clinical effect
- Caution should be exercised when considering concomitant therapy of NSAID and quinolones
- Co-administration with other systemic NSAIDs and steroids may increase the frequency of unwanted effects
Contraindications
- Hypersensitivity to any ingredient of the product
- Peptic ulcer
- Hypersensitivity to Diclofenac
- Contra-indicated in asthmatic patient in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Should be employed only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
- Avoid contact with the eyes or mucus membranes
- Hands should be washed properly after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children