Clofenac DT 46.5 mg (Dispersible Tablet)
Unit Price: ৳ 4.02 (10 x 10: ৳ 402.00)
Strip Price: ৳ 40.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication for the prevention of pain, inflammation, and swelling in otorhinolaryngology
- Post-operative and post-traumatic pain
- Prevention of pain and treatment of inflammation and swelling in urogenital tract, renal and biliary colic
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic properties
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
- Metabolized in the liver
- First pass metabolism
Dosage & Administration
- Diclofenac FC Tablet for adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food
- Diclofenac SR Tablet for adults: 1 tablet daily, taken whole with liquid, preferably at meal times
- Diclofenac Dispersible Tablet for adults: 2-3 tablets daily, maximum daily dose 150 mg
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository for adults: 50 mg suppository 2-3 times daily, maximum daily dose 150 mg
- Diclofenac injection for adults: 1 ampoule daily, may be increased up to 2 ampoules daily in serious cases
- Diclofenac Gel for external use only, 2-4 g applied to the skin 3-4 times daily
Interaction
- Potential interactions with lithium and digoxin
- Increased risk of hemorrhage with anticoagulant therapy
- No influence on clinical effect when given with oral antidiabetic agents
- Cases of nephrotoxicity when given with cyclosporin
- Serious toxicity reported when given with methotrexate and NSAIDs within 24 hours of each other
- Potential convulsions due to an interaction between quinolones and NSAIDs
- Increased frequency of unwanted effects when co-administered with other NSAIDs and steroids
Contraindications
- Hypersensitivity to any ingredient of the products
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
- Contra-indicated in asthmatic patients with specific sensitivities
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Use only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Avoid contact with eyes or mucous membranes
- Hands should be washed properly after application
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children