Algirex 60 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Symptomatic relief of Rheumatoid arthritis (RA)
  • Symptomatic relief of Ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Inhibition of COX-2 decreases signs and symptoms of pain, inflammation, and fever with decreased potential for GI toxicity and effects on platelet aggregation

Dosage & Administration

  • Recommended doses for Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, acute gouty arthritis, and postoperative dental surgery pain
  • Shortest duration and lowest effective daily dose should be used
  • Patient's need for symptomatic relief and response to therapy should be re-evaluated periodically

Interaction

  • Interaction with oral anticoagulants, diuretics, ACE inhibitors, Angiotensin II Antagonists, Acetylsalicylic Acid, Ciclosporin, tacrolimus, Lithium
  • Take without regards to meals

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or active GI bleeding
  • Patients with certain allergic-type reactions to acetylsalicylic acid or NSAIDs including COX-2 inhibitors
  • Pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, children and adolescents under 16 years of age, inflammatory bowel disease, congestive heart failure, hypertension, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation, fatigue, influenza-like symptoms, ecchymosis
  • Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
  • Atrial fibrillation, transient ischaemic attack, chest pain, flushing, cough, dyspnoea, anxiety, mental acuity impaired, paraesthesia, electrolyte disturbance, myalgia, arthralgia
  • Rarely confusion and hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not excreted in human milk
  • Excreted in the milk of lactating rats
  • Women who use Etoricoxib must not breastfeed

Precautions & Warnings

  • Caution in patients at risk of developing gastrointestinal complication with NSAIDs
  • Patients with significant risk factors for cardiovascular events should be treated with caution
  • Monitoring of renal function in patients with impaired renal function
  • Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension, or edema
  • Monitoring of liver function in patients with symptoms and/or signs suggesting liver dysfunction
  • Discontinuation at the first appearance of hypersensitivity or skin rash
  • Caution when co-administering with warfarin or other oral anticoagulants

Overdose Effects

  • Single and multiple doses up to 500 mg and 150 mg/day respectively did not result in significant toxicity
  • Usual supportive measures in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store at a temperature of below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions about Algirex 60 mg Tablet

  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming tendencies
  • Breast-feeding warnings
  • Safety with alcohol
  • Safety to drive while on this medicine
  • Effect on kidney function
  • Effect on liver function
  • Quick Tips

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