Algirex 60 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Etoricoxib |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Symptomatic relief of Rheumatoid arthritis (RA)
- Symptomatic relief of Ankylosing spondylitis
- Symptomatic relief of acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 decreases signs and symptoms of pain, inflammation, and fever with decreased potential for GI toxicity and effects on platelet aggregation
Dosage & Administration
- Recommended doses for Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, acute gouty arthritis, and postoperative dental surgery pain
- Shortest duration and lowest effective daily dose should be used
- Patient's need for symptomatic relief and response to therapy should be re-evaluated periodically
Interaction
- Interaction with oral anticoagulants, diuretics, ACE inhibitors, Angiotensin II Antagonists, Acetylsalicylic Acid, Ciclosporin, tacrolimus, Lithium
- Take without regards to meals
Contraindications
- Hypersensitivity to active substance or excipients
- Active peptic ulceration or active GI bleeding
- Patients with certain allergic-type reactions to acetylsalicylic acid or NSAIDs including COX-2 inhibitors
- Pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, children and adolescents under 16 years of age, inflammatory bowel disease, congestive heart failure, hypertension, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation, fatigue, influenza-like symptoms, ecchymosis
- Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
- Atrial fibrillation, transient ischaemic attack, chest pain, flushing, cough, dyspnoea, anxiety, mental acuity impaired, paraesthesia, electrolyte disturbance, myalgia, arthralgia
- Rarely confusion and hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Not excreted in human milk
- Excreted in the milk of lactating rats
- Women who use Etoricoxib must not breastfeed
Precautions & Warnings
- Caution in patients at risk of developing gastrointestinal complication with NSAIDs
- Patients with significant risk factors for cardiovascular events should be treated with caution
- Monitoring of renal function in patients with impaired renal function
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension, or edema
- Monitoring of liver function in patients with symptoms and/or signs suggesting liver dysfunction
- Discontinuation at the first appearance of hypersensitivity or skin rash
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- Single and multiple doses up to 500 mg and 150 mg/day respectively did not result in significant toxicity
- Usual supportive measures in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store at a temperature of below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Algirex 60 mg Tablet
- Duration of effect
- Onset of action
- Pregnancy warnings
- Habit forming tendencies
- Breast-feeding warnings
- Safety with alcohol
- Safety to drive while on this medicine
- Effect on kidney function
- Effect on liver function
- Quick Tips