Aroxia 90 mg (Tablet)

Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Etoricoxib
Company Ad din pharmaceuticals ltd
Also available as
Aroxia 60 mg tablet Aroxia 120 mg tablet

Indications

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Potent COX-2 inhibitor
  • Orally active
  • Inhibition of COX-2 decreases pain, inflammation, and fever
  • Selective inhibition without effects on COX-1
  • Dose-dependent inhibition of COX-2

Dosage & Administration

  • Recommended doses for different conditions
  • Variation of dosage based on patient response
  • Shortest duration and lowest effective daily dose usage

Interaction

  • With oral anticoagulants
  • With diuretics, ACE inhibitors, and Angiotensin II Antagonists
  • With acetylsalicylic acid for cardiovascular prophylaxis
  • Potential interaction with ciclosporin, tacrolimus, and lithium

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or gastrointestinal bleeding
  • History of allergic-type reactions after taking NSAIDs including COX-2 inhibitors
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension, ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended for women attempting to conceive
  • Excretion in the milk of lactating rats
  • Not to be used during breastfeeding

Precautions & Warnings

  • Caution with patients at risk of gastrointestinal complication with NSAIDs
  • Consideration for patients with significant cardiovascular risk factors
  • Monitoring of renal function
  • Caution in patients with cardiac failure, left ventricular dysfunction, or hypertension
  • Monitoring and discontinuation in case of liver dysfunction
  • Discontinuation at the first appearance of hypersensitivity signs
  • Possible masking of fever and inflammation signs
  • Caution with co-administration of warfarin or other oral anticoagulants

Overdose Effects

  • No significant toxicity observed up to specific doses
  • Usual supportive measures in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image Source: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

Common Questions

  • What is Aroxia 90 mg Tablet?
  • Uses of Aroxia 90 mg Tablet
  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit-forming tendencies
  • Breastfeeding warnings
  • Safety with alcohol
  • Safety for driving
  • Effect on kidney function
  • Effect on liver function
  • Quick Tips for usage

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