Aroxia 120 mg (Tablet)

Unit Price: ৳ 11.50 (3 x 10: ৳ 345.00)
Strip Price: ৳ 115.00

Medicine Details

Title

  • Aroxia 120 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Indications

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Selective COX-2 inhibitor
  • Inhibition of prostaglandin-mediated pain, inflammation, and fever

Dosage & Administration

  • Adult and adolescent over 16 years
  • Recommended doses for different conditions
  • Short-term treatment for dental surgery pain
  • Need for periodic re-evaluation
  • Shortest duration and lowest effective dose usage

Interaction

  • Effects on oral anticoagulants
  • Effects on diuretics and antihypertensive drugs
  • Concomitant use with acetylsalicylic acid
  • Potential nephrotoxic effect with ciclosporin and tacrolimus
  • Increase in lithium plasma levels

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or gastrointestinal bleeding
  • Adverse reactions to acetylsalicylic acid or NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension
  • Established cardiovascular diseases

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Chest pain
  • Anxiety
  • Myalgia and arthralgia
  • Rarely confusion and hallucinations

Pregnancy & Lactation

  • Not recommended for women attempting to conceive
  • Excretion in human milk
  • Excretion in lactating rats

Precautions & Warnings

  • Caution with patients at risk of gastrointestinal complications
  • Consideration for patients with significant cardiovascular risk factors
  • Possible reduction in prostaglandin formation and renal blood flow
  • Exercise caution in patients with cardiac failure, hypertension, and edema
  • Monitoring for symptoms and signs of liver dysfunction
  • Discontinuation at the first sign of hypersensitivity
  • Possible masking of fever and signs of inflammation
  • Caution with co-administration with warfarin or other oral anticoagulants

Overdose Effects

  • Administration of single and multiple doses
  • Usual supportive measures in the event of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature below 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular formula: C18H15ClN2O2S

Duration of Effect

  • 20-24 hours

Onset of Action

  • Within 1-2 hours of administration
  • Faster onset if taken without food

Pregnancy Warnings

  • Consultation required for pregnant women

Habit Forming

  • No habit forming tendencies

Breastfeeding Warnings

  • Not recommended for breastfeeding mothers

Alcohol Safety

  • Unsafe to consume with alcohol

Driving Safety

  • May affect patient's alertness

Kidney Function

  • Caution in patients with kidney disease
  • Strictly not recommended in severe kidney disease

Liver Function

  • Caution in patients with liver disease
  • Strictly not recommended in severe liver disease

Quick Tips

  • Relieves pain and inflammation
  • May cause fewer stomach problems compared to other NSAIDs
  • May cause dizziness and fatigue
  • Regular monitoring of blood pressure
  • Inform doctor about medical history
  • Regular blood tests for long-term treatment
  • Not to be taken during pregnancy, planning to conceive, or breastfeeding

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