Artorix 60 mg (Tablet)

Unit Price: ৳ 7.00 (30's pack: ৳ 210.00)

Medicine Details

Title

  • Artorix 60 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Indications

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Selective inhibition of COX-2 decreases clinical signs and symptoms
  • No inhibition of COX-1 at doses up to 150 mg daily

Dosage & Administration

  • Adult and adolescent over 16 years
  • Recommended doses for different conditions
  • Short-term treatment for postoperative dental surgery pain
  • Monitoring cardiovascular risks and response to therapy periodically

Interaction

  • Interactions with oral anticoagulants, diuretics, ACE inhibitors, Angiotensin II Antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, and lithium
  • Take without regards to meals

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • Pregnancy and lactation
  • Severe hepatic and renal dysfunction
  • Inflammatory bowel disease, congestive heart failure, hypertension
  • Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation, fatigue, influenza-like symptoms, ecchymosis
  • Commonly dry mouth, taste disturbance, mouth ulcer, appetite and weight change
  • Rarely confusion and hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not known excretion in human milk, excreted in the milk of lactating rats
  • Women who use Artorix must not breastfeed

Precautions & Warnings

  • Caution with elderly, prior history of gastrointestinal disease, significant risk factors for cardiovascular events
  • Caution with renal function, cardiac failure, liver dysfunction, hypersensitivity
  • May mask fever and other signs of inflammation
  • Exercise caution when co-administering with warfarin or other oral anticoagulants

Overdose Effects

  • Up to 500 mg single dose and 150 mg/day multiple doses did not result in significant toxicity
  • Usual supportive measures to be employed in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store at a temperature of below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions about Artorix 60 mg Tablet

  • Selective COX-2 inhibitor primarily responsible for pain, inflammation, and fever
  • Indicated for Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
  • Duration of effect lasts for an average of 20-24 hours
  • Onset of action can be observed within 1-2 hours
  • Not recommended for pregnant and breastfeeding women
  • No habit-forming tendencies reported
  • Unsafe to consume with alcohol
  • Affects alertness and driving, caution with kidney and liver function
  • Quick Tips for usage and monitoring

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