Cox-E 120 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Etoricoxib
Company Popular pharmaceuticals ltd
Also available as
Cox e 60 mg tablet Cox e 90 mg tablet

Title

  • Cox-E 120 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Dental surgery pain

Pharmacology

  • Potent COX-2 specific inhibitor
  • Inhibition of COX-2 decreases clinical signs and symptoms
  • Decreased potential for GI toxicity
  • Clinical dose range
  • Dose-dependent inhibition of COX-2 without inhibition of COX-1

DosageAndAdministration

  • 30 mg once daily for Osteoarthritis
  • 90 mg once daily for Rheumatoid arthritis and Ankylosing spondylitis
  • 120 mg once daily for Acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery
  • Additional postoperative analgesia may be required
  • Need for symptomatic relief and response should be re-evaluated periodically

Interaction

  • With oral anticoagulants
  • With Diuretics, ACE inhibitors, and Angiotensin II Antagonists
  • With Acetylsalicylic Acid
  • With Ciclosporin and tacrolimus
  • With Lithium
  • Take without regards to meals

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or GI bleeding
  • Bronchospasm, acute rhinitis, nasal polyps, angioneurotic edema
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension
  • Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

SideEffects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Paresthesia
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

PregnancyAndLactation

  • Not recommended in women attempting to conceive
  • Excreted in the milk of lactating rats
  • Women must not breastfeed if using

PrecautionsAndWarnings

  • Caution with patients at risk of developing a gastrointestinal complication
  • Patients with significant risk factors for cardiovascular events
  • Caution with renal function
  • Caution with cardiac failure, left ventricular dysfunction, or hypertension
  • Monitoring of liver function and discontinuation in case of hepatic insufficiency
  • Discontinuation at the first appearance of hypersensitivity
  • Effect of masking fever and other signs of inflammation
  • Caution when co-administering with warfarin or other oral anticoagulants

OverdoseEffects

  • Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
  • Usual supportive measures in case of overdose

TherapeuticClass

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

StorageConditions

  • Store below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

ChemicalStructure

  • Molecular Formula: C18H15ClN2O2S

CommonQuestions

  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming
  • Breast-feeding warnings
  • Safety with alcohol
  • Safety to drive
  • Effect on kidney function
  • Effect on liver function
  • Quick Tips

Related Brands