Coxet 90 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Moderate pain associated with dental surgery
Pharmacology
- Potent, orally active COX-2 specific inhibitor
- Inhibition of COX-2
- Decreased potential for GI toxicity
- Dose-dependent inhibition of COX-2 without inhibition of COX-1
Dosage & Administration
- Recommended doses for different conditions
- Short-term treatment duration
- Need for re-evaluation of symptomatic relief
Interaction
- Interaction with oral anticoagulants
- Potential reduction of diuretics and antihypertensive drugs' effect
- Concomitant use with low-dose acetylsalicylic acid
- Potential interaction with ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or Gl bleeding
- History of allergic-type reactions to NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Age under 16 years
- Inflammatory bowel disease
- Congestive heart failure
- Uncontrolled hypertension
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Mental acuity impaired
- Paraesthesia
- Electrolyte disturbance
- Myalgia and arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excreted in lactating rats' milk
- Not safe for breastfeeding
Precautions & Warnings
- Caution with patients at risk of GI complications
- Consideration for patients with significant cardiovascular event risk factors
- Potential renal impairment and requirement for monitoring
- Caution with cardiac failure, left ventricular dysfunction, hypertension, and pre-existing edema
- Monitoring of liver function and discontinuation upon hepatic insufficiency or hypersensitivity signs
Overdose Effects
- No significant toxicity at high doses
- Standard supportive measures in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Coxet 90 mg Tablet
- Indication for symptomatic relief of pain and inflammation
- Duration of effect
- Onset of action
- Pregnancy warnings
- Non-habit forming
- Breastfeeding warnings
- Safety with alcohol
- Impact on driving
- Impact on kidney function
- Impact on liver function
- Quick tips for usage