Coxfree 60 mg (Tablet)
Unit Price: ৳ 7.02 (30's pack: ৳ 210.60)
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Title
- Coxfree 60 mg Tablet
Categories
- Medicine
- Pharmaceutical
Description
- Coxfree is indicated for the symptomatic relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, and acute gouty arthritis. It is also used for the short-term treatment of moderate pain associated with dental surgery. Etoricoxib, the active ingredient, is a potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor. It is classified as a non-steroidal anti-inflammatory drug (NSAID) and should be stored at a temperature below 30°C, protected from light and moisture.
Dimensions
- 60 mg tablet
Color options
- None
Functions
- Symptomatic relief of osteoarthritis
- Symptomatic relief of rheumatoid arthritis
- Symptomatic relief of ankylosing spondylitis
- Symptomatic relief of acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Materials
- Etoricoxib
Technical specifications
- Molecular Formula: C18H15ClN2O2S
Design elements
- Chemical Structure
- Tablet
Usability features
- Selective COX-2 inhibition
- Dose-dependent COX-2 inhibition
- Decreased potential for GI toxicity
- Limited duration for postoperative dental surgery pain
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Dental surgery pain
Pharmacology
- Potent, orally active COX-2 specific inhibitor
- Inhibition of prostaglandin synthesis
- Decreased potential for GI toxicity
- Dose-dependent inhibition of COX-2
Dosage and administration
- Recommended doses for different indications
- Shortest duration and lowest effective daily dose usage recommendation
- Need for periodic re-evaluation of symptomatic relief and therapy response
Interaction
- Interaction with oral anticoagulants
- Interaction with diuretics, ACE inhibitors, and Angiotensin II Antagonists
- Concomitant use with acetylsalicylic acid for cardiovascular prophylaxis
- Potential interaction with ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active gastrointestinal bleeding
- History of allergic-type reactions to acetylsalicylic acid or NSAIDs
- Pregnancy, lactation, severe hepatic dysfunction, and estimated renal creatinine clearance <30 ml/min
- Age under 16 years, inflammatory bowel disease, and congestive heart failure
Side effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy and lactation
- Not recommended during attempts to conceive
- Excretion in lactating rats
- Strict avoidance of breastfeeding
Precautions and warnings
- Caution for patients at risk of gastrointestinal complications with NSAIDs
- Special consideration for patients with significant cardiovascular risk factors
- Monitoring of renal function for patients at risk
- Caution for patients with history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring for patients with symptoms suggesting liver dysfunction
- Discontinuation at the first appearance of hypersensitivity signs
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose effects
- No significant toxicity observed at specified doses
- Usual supportive measures recommended in case of overdose
Therapeutic class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of reach of children
Common questions
- What is Coxfree 60 mg Tablet?
- What are the uses of Coxfree 60 mg Tablet?
- Duration of effect of Coxfree 60 mg Tablet
- Onset of action of Coxfree 60 mg Tablet
- Pregnancy warnings of Coxfree 60 mg Tablet
- Habit-forming tendencies of Coxfree 60 mg Tablet
- Breast-feeding warnings of Coxfree 60 mg Tablet
- Safety with alcohol
- Safety to drive while on this medicine
- Effect on kidney function
- Effect on liver function
- Quick Tips