Coxfree 90 mg (Tablet)

Unit Price: ৳ 12.03 (30's pack: ৳ 360.90)

Medicine Details

Title

  • Coxfree 90 mg Tablet

Categories

  • Medications
  • Pain Relief

Description

  • Coxfree is indicated for the symptomatic relief of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gouty arthritis, as well as for the short-term treatment of moderate pain associated with dental surgery. It belongs to the therapeutic class of non-steroidal anti-inflammatory drugs (NSAIDs). The active substance is etoricoxib, a potent orally active cyclooxygenase-2 (COX-2) specific inhibitor.

Dose and administration

  • Recommended doses for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, and postoperative dental surgery pain
  • The shortest duration possible and the lowest effective daily dose should be used
  • Re-evaluate the need for symptomatic relief and response to therapy periodically, especially in patients with osteoarthritis

Pharmacology

  • Etoricoxib is a potent COX-2 specific inhibitor within the clinical dose range, selectively inhibits COX-2, decreasing clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation.

Interaction

  • Interaction with oral anticoagulants, diuretics, ACE inhibitors, angiotensin II antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, and lithium
  • Take without regards to meals

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • Patients with specific allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 inhibitors
  • Pregnancy and lactation
  • Severe hepatic dysfunction and estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Various medical conditions including inflammatory bowel disease, congestive heart failure, hypertension, established cardiovascular diseases

Side effects

  • List of potential side-effects including palpitation, fatigue, influenza-like symptoms, ecchymosis, dry mouth, taste disturbance, mental acuity impaired, myalgia, arthralgia, confusion, hallucinations

Pregnancy lactation

  • Not recommended in women attempting to conceive or during lactation due to unknown excretion in human milk and excretion in lactating rats

Precautions warnings

  • Caution in patients at risk of GI complications with NSAIDs, elderly patients, and those with prior history of gastrointestinal disease
  • Caution in patients with significant risk factors for cardiovascular events
  • Monitoring of renal function and caution in patients with cardiac failure, left ventricular dysfunction, hypertension, or pre-existing edema
  • Monitoring of liver function and discontinuation if signs of hepatic insufficiency occur
  • Discontinuation at the first appearance of specific symptoms and/ or signs
  • Potential for masking fever and other signs of inflammation when co-administered with warfarin or other oral anticoagulants

Overdose effects

  • Information on potential overdose effects and recommended supportive measures

Storage conditions

  • Storage instructions at temperatures below 30°C, protection from light and moisture, and keeping out of reach of children

Chemical structure

  • Molecular formula and chemical structure image of etoricoxib

Common questions

  • FAQs about Coxfree 90 mg Tablet: uses, duration of effect, onset of action, pregnancy warnings, habit forming tendencies, breast-feeding warnings, safety with alcohol and driving, effect on kidney and liver function, and quick tips for usage

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