Coxfree 120 mg (Tablet)
Unit Price: ৳ 14.04 (20's pack: ৳ 280.80)
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Indications
- Relief of Osteoarthritis (OA)
- Relief of Rheumatoid arthritis (RA)
- Relief of Ankylosing spondylitis
- Relief of pain and inflammation associated with acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent COX-2 specific inhibitor
- Orally active
- Inhibition of COX-2 without inhibition of COX-1 at clinical dose range
Dosage & Administration
- Recommended doses for different conditions
- Adjustment of dose based on patient response
- Shortest duration and lowest effective dose usage
- Need for periodic re-evaluation of symptomatic relief and response to therapy
Interaction with Medicine
- Effect on oral anticoagulants
- Interaction with diuretics, ACE inhibitors, and Angiotensin II Antagonists
- Concomitant use with acetylsalicylic acid
- Potential interaction with ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active gastrointestinal (GI) bleeding
- History of bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions to NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance below 30 ml/min
- Inflammatory bowel disease
- Congestive heart failure
- Uncontrolled hypertension
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excretion in rat milk
- Prohibition of breastfeeding while using the product
Precautions & Warnings
- Caution with patients at risk of GI complications
- Consideration of cardiovascular risk factors in patients
- Monitoring of renal function
- Exercise caution in patients with history of cardiac failure, left ventricular dysfunction, hypertension, and edema
- Monitoring of liver function and discontinuation of product upon signs of hepatic insufficiency
- Discontinuation at first appearance of hypersensitivity signs
- Potential masking of fever and other signs of inflammation
- Caution in co-administration with warfarin or other oral anticoagulants
Overdose Effects
- No significant toxicity observed in single or multiple doses
- Usual supportive measures and clinical monitoring in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Temperature below 30°C
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Coxfree 120 mg Tablet
- Duration of effect
- Onset of action
- Pregnancy warnings
- Habit forming tendencies
- Advice on alcohol consumption
- Effects on driving, kidney, and liver function
- Quick Tips for usage
Color Options
- White
- Off-white
- Yellow
- Blue
Packaging Options
- Blister packs
- Bottles
Usability Features
- Oral administration
- Daily dosing regimen
- Relief duration of 20-24 hours
Material
- Active substance - Etoricoxib
- Excipients: to be determined from product label
Age Restrictions
- Adult and adolescent over 16 years only
Formulation
- Tablet
Dimensions
- Standard tablet size
Manufacturer Information
- Manufacturer name
- Contact details for inquiries
Primary Function
- Relief of pain and inflammation
Technical Specifications
- Clinical dose range
- Inhibition of COX-1 and COX-2 at specific doses
Design Elements
- Branding logo
- Imprinted product details on tablet
Dosage Adjustment
- Based on patient response and symptom relief
External Packaging
- Product name and branding
- Dosage strength
- Package size
Expiry Date
- Disposal guidance for expired products
User Guide Availability
- Online resource or printed booklet
Safety Information
- First aid measures in case of accidental ingestion
Certifications
- Regulatory approval details
Shelf Life
- Details on product stability and expiry period
Hazards
- Side effect warnings
- Cautionary statements for contraindications
Batch Number
- Identification for product traceability and quality control
Storage Instructions
- Temperature and environmental requirements
Product Variants
- Different dosage strengths
Efficacy
- Clinical trial data on relief and symptom management
Administration Route
- Oral intake
Legal Disclaimers
- Liability statements and usage disclaimers
Production Date
- Manufacturing details
Serving Size
- Single tablet per dose
Allergen Information
- Excipient details for allergen risks
Emergency Contact Information
- Contact details for poison control or emergencies
Lab Testing Information
- Quality control and assurance details
Price Range
- Different pricing options based on package size and variants
Relevant Research Studies
- Published studies on product efficacy and safety
Clinical Guidelines
- Usage guidelines for healthcare professionals