Coxitor 60 mg (Tablet)

Unit Price: ৳ 7.05 (3 x 10: ৳ 211.50)
Strip Price: ৳ 70.50

Medicine Details

Category Details
Generic Etoricoxib
Company Beacon pharmaceuticals plc
Also available as
Coxitor 90 mg tablet Coxitor 120 mg tablet

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Potent inhibition of COX-2
  • Selective inhibition of COX-2
  • Decreased potential for GI toxicity
  • Dose-dependent inhibition of COX-2 without inhibition of COX-1

Dosage & Administration

  • Recommended doses for different conditions
  • Special considerations for cardiovascular risks
  • Re-evaluation of patient's need for symptomatic relief and response to therapy

Interaction

  • Interaction with oral anticoagulants
  • Potential reduction of the effect of diuretics and other antihypertensive drugs
  • Concomitant use with acetylsalicylic acid
  • Possible nephrotoxic effect with ciclosporin and tacrolimus
  • Impact on lithium renal excretion

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or GI bleeding
  • Allergic-type reactions after taking acetylsalicylic acid or NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension
  • Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Anxiety
  • Myalgia and arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Excretion in human milk
  • Excretion in the milk of lactating rats
  • Incompatibility with breastfeeding

Precautions & Warnings

  • Caution in patients at risk of GI complications
  • Consideration for patients with significant risk factors for cardiovascular events
  • Monitoring of renal function
  • Exercise caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension
  • Monitoring of liver function
  • Discontinuation in case of hypersensitivity
  • Potential masking of fever and other signs of inflammation
  • Caution when co-administering with warfarin or other oral anticoagulants

Overdose Effects

  • No significant toxicity reported up to 500 mg single dose or 150 mg/day multiple doses
  • Employment of usual supportive measures in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature below 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions about Coxitor 60 mg Tablet

  • Selective COX-2 inhibitor
  • Indicated for relief of Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming tendencies
  • Breast-feeding warnings
  • Safety with alcohol
  • Effect on driving
  • Effect on kidney function
  • Effect on liver function
  • Quick Tips

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