Coxpain 60 mg (Tablet)

Unit Price: ৳ 8.02 (30's pack: ৳ 240.72)

Medicine Details

Title

  • Coxpain 60 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Indications

  • Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Inhibition of COX-2 decreases signs and symptoms of pain and inflammation with decreased potential for Gl toxicity and effects on platelet aggregation

Dosage & Administration

  • 30 mg once daily for Osteoarthritis
  • 90 mg once daily for Rheumatoid arthritis and Ankylosing spondylitis
  • 120 mg once daily for Acute gouty arthritis
  • Short-term treatment of 90 mg once daily for dental surgery pain, limited to a maximum of 3 days

Interaction

  • Increased prothrombin time when co-administered with oral anticoagulants
  • May reduce the effect of diuretics and other antihypertensive drugs when co-administered
  • Can be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active Gl bleeding
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Inflammatory bowel disease
  • Congestive heart failure, hypertension, and cardiovascular diseases

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Transient ischaemic attack
  • Anxiety
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended for women attempting to conceive
  • Not recommended for breastfeeding mothers

Precautions & Warnings

  • Caution advised for patients at risk of developing gastrointestinal complications with NSAIDs
  • Patients with significant risk factors for cardiovascular events should be treated with caution
  • May cause reduction in prostaglandin formation and impair renal function
  • Caution in patients with history of cardiac failure, left ventricular dysfunction, or hypertension
  • Monitoring of renal and hepatic functions is recommended

Overdose Effects

  • No significant toxicity reported up to 150 mg/day for 21 days
  • Supportive measures should be employed in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image: (link to image)

Common Questions & Answers

  • What is Coxpain 60 mg Tablet?
  • What are the uses of Coxpain 60 mg Tablet?
  • Duration of effect of Coxpain 60 mg Tablet
  • Onset of action of Coxpain 60 mg Tablet
  • Pregnancy and breastfeeding warnings
  • Habit forming tendencies
  • Safety with alcohol
  • Safety to drive while on this medicine
  • Effect on kidney and liver function
  • Quick tips for usage

Food & Others Interaction

  • Take without regards to meals

Drug Interaction with ACE inhibitors

  • May reduce the effect of ACE inhibitors when co-administered

Drug Interaction with Angiotensin II Antagonists

  • May reduce the effect of Angiotensin II Antagonists when co-administered

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