Coxpain 90 mg (Tablet)
Unit Price: ৳ 12.04 (20's pack: ৳ 240.72)
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Novo healthcare and pharma ltd |
| Also available as |
Title
- Coxpain 90 mg Tablet
Categories
- Medicine
- Pharmaceuticals
Description
- Coxpain is indicated for the symptomatic relief of osteoarthritis (OA), rheumatoid arthritis (RA), ankylosing spondylitis, acute gouty arthritis, and short-term treatment of moderate pain associated with dental surgery.
Dosage
- Adult and adolescent over 16 years
- Osteoarthritis - 30 mg once daily; may increase to 60 mg
- Rheumatoid arthritis - 90 mg once daily
- Ankylosing spondylitis - 90 mg once daily
- Acute gouty arthritis - 120 mg once daily for 8 days
- Postoperative dental surgery pain - 90 mg once daily; maximum of 3 days
Contraindications
- Hypersensitivity to active substance or excipients
- Active peptic ulceration or gastrointestinal bleeding
- Bronchospasm or allergic reactions to acetylsalicylic acid or NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction or renal impairment
- Inflammatory bowel disease, congestive heart failure, hypertension, ischaemic heart disease
Side effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
Pregnancy lactation
- Not recommended in women attempting to conceive
- Not known about excretion in human milk
- Women who use it must not breastfeed
Precautions warnings
- Caution in elderly and patients with prior history of gastrointestinal disease
- Caution in patients with significant cardiovascular risk factors
- Monitoring of renal function
- Caution in patients with history of cardiac failure or hypertension
- Monitoring of liver function
- Discontinue at the first appearance of hypersensitivity
Drug interaction
- Oral anticoagulants - may increase prothrombin time
- Diuretics and ACE inhibitors - may reduce their effect
- Acetylsalicylic Acid - can be used concomitantly at low doses for cardiovascular prophylaxis
- Ciclosporin and tacrolimus - may increase nephrotoxic effect
- Lithium - decrease lithium renal excretion
Duration of effect
- 20-24 hours
Onset of action
- 1-2 hours
- Faster if taken without food
Pregnancy warnings
- Not recommended
- Consult doctor before using
Habit forming
- No habit forming tendencies reported
Breastfeeding warnings
- Not recommended
- Use only when potential benefits outweigh risks
- Consult doctor before use
Safe with alcohol
- Unsafe to consume with alcohol
Driving while on medicine
- May affect alertness
- Patient must avoid driving
Affect on kidney function
- Caution in patients with kidney disease
- Adjustment of dose might be needed
- Strictly not recommended in severe kidney disease
Affect on liver function
- Caution in patients with liver disease
- Adjustment of dose might be needed
- Strictly not recommended in severe liver disease
Storage conditions
- Store at a temperature of below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical structure
- Molecular formula: C18H15ClN2O2S
- Chemical structure image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg
Therapeutic class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Precaution quick tips
- Helps relieve pain and inflammation
- May cause fewer stomach problems compared to other NSAIDs
- May cause dizziness and fatigue
- Do not consume alcohol while on treatment
- Regularly monitor blood pressure during treatment
- Inform doctor of medical history before use
- Regular liver function tests during long-term treatment
- Do not take if pregnant, planning to conceive, or breastfeeding
Overdose effects
- Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
- Usual supportive measures recommended in case of overdose