Ecox 90 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Alco pharma ltd |
| Also available as |
Title
Ecox 90 mg Tablet
Categories
- Pain Relief
- Anti-Inflammatory
- Medication
Description
Ecox is a selective COX-2 inhibitor indicated for the symptomatic relief of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, and short-term treatment of moderate pain associated with dental surgery. It is a non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2 without inhibiting COX-1 at doses up to 150 mg daily, with decreased potential for gastrointestinal toxicity and effects on platelet aggregation. It is available in 90 mg tablets and should be used with caution in patients with cardiovascular risks, renal impairment, hepatic dysfunction, and gastrointestinal complications.
Dimensions
2cm x 1cm x 1cm
Color Options
- White
Dosage
- Adult:
- Osteoarthritis: 30 mg once daily, increased to 60 mg for insufficient relief
- Rheumatoid arthritis: 90 mg once daily
- Ankylosing spondylitis: 90 mg once daily
- Acute gouty arthritis: 120 mg once daily for 8 days
- Postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days
- Adolescent over 16 years: Dosage similar to adults
Interaction
- Medicine:
- Oral anticoagulants
- Diuretics, ACE inhibitors and Angiotensin II Antagonists
- Acetylsalicylic Acid
- Ciclosporin and tacrolimus
- Lithium
- Food & Others: Take without regards to meals
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Active peptic ulceration or active gastrointestinal (GI) bleeding
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Patients with hypertension
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Mental acuity impaired
- Paraesthesia
- Electrolyte disturbance
- Myalgia and arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
Not recommended for women attempting to conceive or lactating women
Precautions & Warnings
- Caution in patients at risk of gastrointestinal complication with NSAIDs
- Caution in patients with significant risk factors for cardiovascular events
- Monitoring of renal function in patients with reduced renal blood flow
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function and discontinuation in case of hepatic insufficiency
- Discontinuation at the first appearance of hypersensitivity signs
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
No significant toxicity observed up to 150 mg/day for 21 days; employ usual supportive measures in case of overdose
Therapeutic Class
Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Store below 30°C, protect from light & moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions
- Duration of effect
- Onset of action
- Pregnancy warnings
- Habit forming nature
- Breastfeeding warnings
- Safety with alcohol
- Safety to drive
- Effect on kidney function
- Effect on liver function