Eflam 90 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Apex pharmaceuticals ltd |
| Also available as |
Indications
- Osteoarthritis (OA)
- Rheumatoid arthritis (RA)
- Ankylosing spondylitis
- Acute gouty arthritis
- Moderate pain associated with dental surgery
Mode of Action
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 decreases pain, inflammation, and fever
- Selective inhibition of COX-2 decreases potential for GI toxicity and effects on platelet aggregation
Dosage & Administration
- Recommended doses for different conditions: 30mg-120mg once daily
- Short-term treatment for dental surgery pain
- Consideration for cardiovascular risks and lowest effective dose
Interaction
- Interaction with oral anticoagulants, diuretics, ACE inhibitors, angiotensin II antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, lithium
- Take without regards to meals
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or GI bleeding
- Pregnancy and lactation
- Severe hepatic dysfunction, estimated renal creatinine clearance <30ml/min
- Inflammatory bowel disease, congestive heart failure, hypertension, established cardiovascular diseases
Side Effects
- Palpitation, fatigue, influenza-like symptoms, ecchymosis
- Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
- Atrial fibrillation, transient ischaemic attack, chest pain, flushing
- Cough, dyspnoea, epistaxis, anxiety, impaired mental acuity
- Electrolyte disturbance, myalgia, arthralgia
- Rarely confusion, hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excreted in the milk of lactating rats
- Breastfeeding not recommended
Precautions & Warnings
- Caution in elderly, patients with prior GI disease, cardiovascular risk factors
- Consideration for renal function, cardiac failure, left ventricular dysfunction, hypertension
- Monitoring for liver function, hypersensitivity, fever and inflammation
- Co-administration with warfarin or oral anticoagulants
Overdose Effects
- No significant toxicity observed with single doses up to 500mg and multiple doses up to 150mg/day
- Usual supportive measures recommended in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C, protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Duration of Effect
- Average duration of 20-24 hours
Onset of Action
- Effect observed within 1-2 hours of administration
Pregnancy Warnings
- Consult doctor before use
Habit Forming
- No habit-forming tendencies reported
Breastfeeding Warnings
- Not recommended, consult doctor before use
Safe with Alcohol
- Unsafe to consume with alcohol
Safe to Drive
- May affect alertness, avoid driving
Affect on Kidney Function
- Caution in patients with kidney disease
Affect on Liver Function
- Caution in patients with liver disease
Quick Tips
- Helps relieve pain and inflammation
- May cause fewer stomach problems compared to other NSAIDs
- May cause dizziness and fatigue
- Avoid alcohol consumption
- Regular blood pressure monitoring
- Inform doctor of medical history
- Doctor may request regular liver function tests
- Avoid if pregnant, planning to conceive, or breastfeeding