Etoriflex 90 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
Category | Details |
---|---|
Generic | Etoricoxib |
Company | Somatec pharmaceuticals ltd |
Also available as |
Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 decreases clinical signs and symptoms with decreased potential for gastrointestinal toxicity and effects on platelet aggregation
- Selective inhibition of COX-2 by etoricoxib decreases pain, inflammation, and fever
Dosage & Administration
- Recommended doses for different conditions
- Possible need for increased dose in some patients for insufficient relief from symptoms
- Consideration of cardiovascular risks and lowest effective daily dose
Interaction
- Interaction with oral anticoagulants, diuretics, ACE inhibitors, angiotensin II antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, and lithium
- Recommendation to take without regards to meals
Contraindications
- Hypersensitivity to active substance or excipients
- Active peptic ulceration or gastrointestinal bleeding
- History of allergic-type reactions after taking acetylsalicylic acid or NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance
- Inflammatory bowel disease
- Congestive heart failure
- Hypertension
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Mental acuity impaired
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Not known whether excreted in human milk
- Excreted in the milk of lactating rats
- Women who use must not breastfeed
Precautions & Warnings
- Caution with elderly and patients with gastrointestinal disease
- Caution with patients at significant risk of cardiovascular events
- Potential impairment of renal function
- Caution with patients with history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function and discontinuation if signs of hepatic insufficiency occur
- Discontinuation at the first appearance of skin rash or any sign of hypersensitivity
- Potential masking of fever and other signs of inflammation
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- No significant toxicity observed with single or multiple doses up to 150 mg/day
- Employment of usual supportive measures in the event of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Etoriflex 90 mg Tablet
- Description of Etoriflex 90 mg Tablet as a selective COX-2 inhibitor
- Uses of Etoriflex 90 mg Tablet for pain relief
- Duration of effect of Etoriflex 90 mg Tablet
- Onset of action of Etoriflex 90 mg Tablet
- Pregnancy warnings of Etoriflex 90 mg Tablet
- Habit forming tendencies
- Breast-feeding warnings
- Safety with alcohol
- Driving precautions
- Effect on kidney function
- Effect on liver function
- Quick tips for usage