Etorix 60 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Rheumatoid arthritis (RA)
- Ankylosing spondylitis
- Pain and signs of inflammation associated with acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Selective inhibition of COX-2 within the clinical dose range
- Decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation
- Did not inhibit gastric prostaglandin synthesis
Dosage & Administration
- Recommended doses for different conditions: 30mg once daily, 60mg once daily, 90mg once daily, 120mg once daily
- Shortest duration possible and lowest effective daily dose should be used
- Re-evaluate periodically, especially in patients with osteoarthritis
Interaction
- Oral anticoagulants: associated with an increase in prothrombin time
- NSAIDs may reduce the effect of diuretics and other antihypertensive drugs
- Can be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis
- Coadministration with ciclosporin or tacrolimus may increase nephrotoxic effect
- Decreases lithium renal excretion and increases lithium plasma levels
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Active peptic ulceration or active gastrointestinal (GI) bleeding
- Patients with certain allergic-type reactions after taking NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure, hypertension, established cardiovascular diseases
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excreted in the milk of lactating rats
- Women who use Etoricoxib must not breastfeed
Precautions & Warnings
- Caution in patients at risk of developing a gastrointestinal complication with NSAIDs
- Treatment in patients with significant risk factors for cardiovascular events after careful consideration
- May cause reduction in prostaglandin formation and impair renal function
- Caution in patients with history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function and discontinuation if signs of hepatic insufficiency occur
Overdose Effects
- Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
- Usual supportive measures in the event of overdose: remove unabsorbed material, employ clinical monitoring, institute supportive therapy
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
- Chemical Structure Image: [Link to the image]
Common Questions
- What is Etorix 60 mg Tablet?
- Duration of effect
- Onset of action
- Pregnancy warnings
- Habit forming
- Breast-feeding warnings
- Safety with alcohol
- Safety to drive
- Effect on kidney function
- Effect on liver function
- Quick Tips for usage