Anzitor 40 mg (Tablet)

Unit Price: ৳ 28.00 (1 x 10: ৳ 280.00)
Strip Price: ৳ 280.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Square pharmaceuticals plc
Also available as
Anzitor 10 mg tablet Anzitor 20 mg tablet

Title

Anzitor 40 mg Tablet

Categories

  • Medicine
  • Pharmaceutical
  • Health

Description

Anzitor is indicated as an adjunct to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in specific diseases. Atorvastatin is a selective inhibitor of HMG-CoA reductase and lowers plasma cholesterol and lipoprotein levels. Anzitor is available in tablet form and belongs to the therapeutic class of Other Anti-anginal & Anti-ischaemic drugs, Statins.

Dimensions

N/A

Color options

N/A

Functions

  • Lowers total cholesterol and LDL cholesterol levels
  • Reduces apolipoprotein B and triglycerides levels
  • Enhances uptake and catabolism of LDL
  • Reduces cardiac ischaemic events
  • Prevents heart attacks
  • Treats hypercholesterolemia and dyslipidemia

Materials

N/A

Technical specifications

  • Absorption: Rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours
  • Distribution: Mean volume of distribution of Atorvastatin is approximately 381 liters. Atorvastatin is 98% bound to plasma proteins.
  • Metabolism: Extensively metabolized to ortho- and parahydroxylated derivatives. In vitro studies suggest the importance of Atorvastatin metabolism by cytochrome P450 3A4.
  • Excretion: Eliminated primarily in bile following hepatic and/or extra-hepatic metabolism.

Design elements

N/A

Usability features

  • Can be taken with or without food
  • Should be used with a standard cholesterol-lowering diet
  • Dosage should be adjusted according to lipid levels within 2 to 4 weeks

Dosage

  • Adults: Usually 10 to 80 mg once daily
  • Children (10-18 years): Initially 10 mg once daily, increased if necessary

Interaction

  • Concurrent Administration:
    • Cyclosporine
    • Fibric acid derivatives
    • Niacin (nicotinic acid)
    • Erythromycin
    • Azole antifungals

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy lactation

  • Pregnancy: Contraindicated during pregnancy; may reduce fetal levels of mevalonate
  • Lactation: Contraindicated during breastfeeding; potential for serious adverse reactions

Precautions warnings

  • Liver function tests should be performed before initiation of treatment
  • Use with caution in patients with substantial alcohol consumption or history of liver disease
  • Therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Special populations

  • Geriatric: Plasma concentrations are higher in healthy elderly subjects
  • Pediatric: Pharmacokinetic data not available
  • Gender: No clinically significant difference in LDL-C reduction between men and women
  • Renal Insufficiency: No influence on plasma concentrations or LDL-C reduction
  • Hemodialysis: Not expected to significantly enhance clearance of Atorvastatin
  • Hepatic Insufficiency: Plasma concentrations are markedly increased in patients with chronic alcoholic liver disease

Overdose effects

Specific treatment is not available for atorvastatin overdose; patient should be treated symptomatically and supportive measures instituted

Storage conditions

Keep in a dry place away from light and heat; keep out of the reach of children

Chemical structure

  • Molecular Formula: C33H35FN2O5

Commonly asked questions

  • What is Anzitor 40 mg Tablet?: Anzitor 40 mg Tablet is a selective inhibitor of HMG-CoA reductase. It is used to avoid heart attacks and Primary Hypercholesterolemia. It is also used to treat conditions such as Mixed Dyslipidemia and Hypertriglyceridemia.
  • How should I take Anzitor 40 mg Tablet?: Anzitor 40 mg Tablet should be taken by mouth once daily, at the same time each day. It can be taken with or without food.
  • What are the uses of Anzitor 40 mg Tablet?: Anzitor 40 mg Tablet is used for the treatment of diseases like Mixed Dyslipidemia and Hypertriglyceridemia. Besides these, it can also be used to treat conditions like heart attacks and Primary Hypercholesterolemia.
  • What are the Side Effects of Anzitor 40 mg Tablet?: This is a list of possible side-effects which may occur due to the constituting ingredients of Anzitor 40 mg Tablet.
  • What are the instructions for storage and disposal of Anzitor 40 mg Tablet?: Anzitor 40 mg Tablet should be stored at room temperature, away from heat and direct light. Keep it away from the reach of children and pets.
  • Is Anzitor 40 mg Tablet used for lowering cholesterol?: Anzitor 40 mg Tablet comes under the class of drugs termed as statins and helps in decreasing the level of lipids or fats.

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