Etox 90 mg (Tablet)

Unit Price: ৳ 12.04 (30's pack: ৳ 361.20)

Medicine Details

Category Details
Generic Etoricoxib
Company Hallmark pharmaceuticals ltd
Also available as

Indications

  • Symptomatic relief of osteoarthritis (OA)
  • Symptomatic relief of rheumatoid arthritis (RA)
  • Symptomatic relief of ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Etoricoxib is a potent orally active COX-2 inhibitor
  • Inhibition of COX-2 reduces clinical signs and symptoms
  • Selective inhibition of COX-2 decreases potential for GI toxicity
  • Etoricoxib does not inhibit gastric prostaglandin synthesis

Dosage & Administration

  • Recommended dose for osteoarthritis: 30mg once daily
  • Recommended dose for rheumatoid arthritis: 90mg once daily
  • Recommended dose for ankylosing spondylitis: 90mg once daily
  • Recommended dose for acute gouty arthritis: 120mg once daily
  • Recommended dose for postoperative dental surgery pain: 90mg once daily, max 3 days
  • Shortest duration possible and lowest effective daily dose should be used

Interactions

  • Interaction with oral anticoagulants
  • Interaction with diuretics, ACE inhibitors, and Angiotensin II Antagonists
  • Can be used concomitantly with low-dose acetylsalicylic acid
  • Potential interaction with ciclosporin and tacrolimus
  • NSAIDs may decrease lithium renal excretion

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active GI bleeding
  • History of allergic-type reactions to NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension, ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended for women attempting to conceive
  • Not known if excreted in human milk
  • Women must not breastfeed while using the product

Precautions & Warnings

  • Caution with patients at risk of gastrointestinal complications
  • Caution with patients at significant risk of cardiovascular events
  • May impair renal function and require monitoring
  • Caution with patients with history of cardiac failure, left ventricular dysfunction, or hypertension

Overdose Effects

  • Single doses of up to 500mg and multiple doses up to 150mg/day did not result in significant toxicity

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions about Etox 90 mg Tablet

  • Selective COX-2 inhibitor
  • Indicated for symptomatic relief of Osteoarthritis (OA), Rheumatoid arthritis (RA), Ankylosing spondylitis
  • Duration of effect: 20-24 hours
  • Onset of action: 1-2 hours, faster if taken without food
  • Pregnancy warnings
  • Not habit forming
  • Breastfeeding warnings
  • Unsafe with alcohol
  • Affects alertness, unsafe to drive
  • Caution in patients with kidney disease
  • Caution in patients with liver disease
  • Quick Tips for usage

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