Ribox 60 mg (Tablet)
Unit Price: ৳ 6.50 (3 x 10: ৳ 195.00)
Strip Price: ৳ 65.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Osteoarthritis (OA)
- Rheumatoid arthritis (RA)
- Ankylosing spondylitis
- Pain relief from acute gouty arthritis
- Moderate pain associated with dental surgery
Pharmacology
- Potent COX-2 inhibitor
- Inhibition of prostaglandin-mediated functions
- Decreased potential for gastric damage and platelet aggregation
- Dose-dependent COX-2 inhibition without affecting COX-1
- No inhibition of gastric prostaglandin synthesis
Dosage & Administration
- Recommended doses for different conditions
- Adjustable doses for some patients
- Short-term treatment for postoperative dental surgery pain
- Emphasis on shortest possible duration and lowest effective daily dose
Interactions
- Interaction with oral anticoagulants
- Potential reduction in diuretic and antihypertensive drug effects
- Concomitant use with low-dose acetylsalicylic acid
- Possible interaction with ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to active substance or excipients
- Active peptic ulceration or gastrointestinal bleeding
- History of allergic-type reactions to NSAIDs
- Pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, age under 16 years, inflammatory bowel disease, congestive heart failure, uncontrolled hypertension, established cardiovascular diseases
Side Effects
- Palpitation, fatigue, influenza-like symptoms
- Taste disturbance, mouth ulcer, appetite and weight change
- Atrial fibrillation, chest pain, flushing, cough, dyspnoea
- Anxiety, impaired mental acuity, electrolyte disturbance
- Myalgia, arthralgia, confusion, hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excretion in rat milk
- Not safe for breastfeeding women
Precautions & Warnings
- Caution with elderly and high-risk patients
- Consideration for cardiovascular risk factors
- Monitoring of renal function, particularly in high-risk patients
- Exercise caution in patients with cardiac or liver dysfunction
- Discontinue at signs of hypersensitivity, hepatitis
- Potential masking of fever and inflammation
- Caution with co-administration with anticoagulants
Overdose Effects
- No significant toxicity at specified doses
- Employ usual supportive measures in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C, protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions about Ribox 60 mg Tablet
- Description of Ribox 60 mg Tablet
- Uses of Ribox 60 mg Tablet
- Duration of effect
- Onset of action
- Pregnancy, habit forming, and breast-feeding warnings
- Safety with alcohol and driving
- Effect on kidney and liver function
- Quick tips for usage