Ribox 90 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Osteoarthritis (OA)
- Rheumatoid arthritis (RA)
- Ankylosing spondylitis
- Acute gouty arthritis
- Moderate pain associated with dental surgery
Pharmacology
- Orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Inhibition of COX-2 decreases pain, inflammation, and fever
- Dose-dependent inhibition of COX-2 without inhibition of COX-1 at clinical doses up to 150 mg daily
Dosage & Administration
- Recommended doses for different conditions
- Patients may require additional postoperative analgesia
- Shortest duration and lowest effective daily dose should be used to minimize cardiovascular risks
Interaction with Medicine
- Effect on oral anticoagulants
- Potential reduction of effect of diuretics and antihypertensive drugs
- Concomitant use with acetylsalicylic acid at low doses for cardiovascular prophylaxis
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active gastrointestinal bleeding
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Dry mouth
- Taste disturbance
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended for women attempting to conceive
- Excreted in the milk of lactating rats
- Not recommended for breastfeeding women
Precautions & Warnings
- Caution advised with NSAID treatment in high-risk patients
- Considering cardiovascular risk factors before treatment
- Monitoring renal function in patients at risk
- Caution in patients with cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring liver function and discontinuing in case of hepatic insufficiency or abnormal liver function tests
- Discontinuation at the first appearance of hypersensitivity signs
- Potential masking of fever and inflammation
- Exercise caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- No significant toxicity observed at specified doses
- Usual supportive measures recommended in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
- Chemical Structure visualization
Common Questions about Ribox 90 mg Tablet
- Information about uses, duration of effect, onset of action, pregnancy warnings, habit-forming tendencies, breast-feeding warnings, safety with alcohol, driving safety, and effects on kidney and liver function
Quick Tips
- Relief of pain and inflammation
- Comparative stomach problems with other NSAIDs
- Potential dizziness, fatigue, and alcohol interaction
- Blood pressure monitoring and history disclosure
- Regular liver function testing during long-term treatment
- Pregnancy and breastfeeding warnings