Rito 120 mg (Tablet)

Unit Price: ৳ 14.05 (2 x 10: ৳ 281.00)
Strip Price: ৳ 140.50

Medicine Details

Category Details
Generic Etoricoxib
Company Opsonin pharma ltd
Also available as
Rito 60 mg tablet Rito 90 mg tablet

Title

  • Rito 120 mg Tablet

Categories

  • Medicine
  • NSAIDs
  • Pain Relief
  • Anti-inflammatory

Description

  • Rito is indicated for the symptomatic relief of Osteoarthritis (OA), Rheumatoid arthritis (RA), Ankylosing spondylitis, and the pain and signs of inflammation associated with acute gouty arthritis. It is also used for the short-term treatment of moderate pain associated with dental surgery. The active ingredient, Etoricoxib, is a potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor.

Dimensions

  • Tablet size: 120 mg

Color options

  • Not applicable

Functions

  • Relieves pain and inflammation
  • Inhibits COX-2
  • Decreases clinical signs and symptoms
  • Reduces the potential for GI toxicity

Materials

  • Active Substance: Etoricoxib

Technical specifications

  • Molecular Formula: C18H15ClN2O2S

Design elements

  • Chemical Structure: C18H15ClN2O2S (Refer to image)
  • Store at a temperature of below 30°C
  • Protect from light & moisture
  • Therapeutic Class: Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Usability features

  • The effect of Rito 120 mg Tablet lasts for an average duration of 20-24 hours.
  • The onset of action can be observed within 1-2 hours of administration, faster if taken without food.

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Symptomatic relief of Rheumatoid arthritis (RA)
  • Symptomatic relief of Ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active COX-2 specific inhibitor
  • Selectively inhibits COX-2 within the clinical dose range
  • Decreases signs and symptoms with decreased potential for GI toxicity
  • Produces dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily

Dosage administration

  • Osteoarthritis: Recommended dose is 30 mg once daily. Increased to 60 mg once daily in some patients for better efficacy
  • Rheumatoid arthritis and Ankylosing spondylitis: Recommended dose is 90 mg once daily
  • Acute gouty arthritis: Recommended dose is 120 mg once daily for 8 days
  • Postoperative dental surgery pain: Recommended dose is 90 mg once daily, limited to a maximum of 3 days

Interactions

  • With medicine: Oral anticoagulants may have increased prothrombin time with Rito
  • With medicine: NSAIDs may reduce the effect of diuretics and other antihypertensive drugs
  • With medicine: Rito can be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis
  • With medicine: Coadministration with ciclosporin, tacrolimus, or lithium should be done with caution
  • With food & others: Take without regards to meals

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • Bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction, Estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease, Congestive heart failure, Hypertension, Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia and arthralgia
  • Confusion
  • Hallucinations

Pregnancy lactation

  • Use of Etoricoxib is not recommended in women attempting to conceive
  • It is not known whether Etoricoxib is excreted in human milk
  • Etoricoxib is excreted in the milk of lactating rats. Women who use Etoricoxib must not breastfeed.

Precautions warnings

  • Caution is advised in patients most at risk of developing a gastrointestinal complication with NSAIDs
  • Patients with significant risk factors for cardiovascular events should be treated with caution
  • Administration may cause a reduction in prostaglandin formation and impair renal function
  • Caution should be exercised in patients with a history of cardiac failure, left ventricular dysfunction, hypertension
  • Patients with symptoms suggesting liver dysfunction should be monitored
  • Rito should be discontinued at the first appearance of signs of hypersensitivity
  • May mask fever and other signs of inflammation
  • Caution should be exercised when co-administering Rito with warfarin or other oral anticoagulants

Overdose effects

  • Administration of single doses up to 500 mg and multiple doses up to 150 mg/day for 21 days did not result in significant toxicity
  • In the event of overdose, employ the usual supportive measures and monitoring

Commonly asked questions

  • What is Rito 120 mg Tablet?
  • What are the uses of Rito 120 mg Tablet?
  • How long is the duration of effect of Rito 120 mg Tablet?
  • What is the onset of action of Rito 120 mg Tablet?
  • Are there any pregnancy warnings of Rito 120 mg Tablet?
  • Is it habit forming of Rito 120 mg Tablet?
  • Are there any breast-feeding warnings of Rito 120 mg Tablet?
  • Is Rito 120 mg Tablet safe with alcohol?
  • Is Rito 120 mg Tablet safe to drive while on this medicine?
  • Does Rito 120 mg Tablet affect kidney function?
  • Does Rito 120 mg Tablet affect liver function?

Storage conditions

  • Store at a temperature of below 30°C
  • Protect from light & moisture
  • Keep out of reach of children

Compound summary

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure: C18H15ClN2O2S

Med ex

  • Rito 120 mg Tablet is found to be unsafe to consume this medicine with alcohol
  • Rito 120 mg Tablet may affect the alertness of the patient taking it. Thus, the patient must avoid driving.

Other information

  • Regular monitoring of blood pressure is necessary while taking this medicine, particularly in the first two weeks after starting treatment.
  • During long-term treatment, regular blood tests to monitor liver function may be required.
  • Do not take this tablet if you are pregnant, planning to conceive, or breastfeeding.

Related Brands