Biocox 90 mg (Tablet)

Unit Price: ৳ 12.03 (3 x 10: ৳ 361.00)
Strip Price: ৳ 120.33

Medicine Details

Category Details
Generic Etoricoxib
Company Biopharma limited

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Symptomatic relief of Rheumatoid arthritis (RA)
  • Symptomatic relief of Ankylosing spondylitis
  • Symptomatic relief of acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Pharmacology

  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
  • Decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation
  • Did not inhibit gastric prostaglandin synthesis

Dosage & Administration

  • Dosage for Osteoarthritis: 30 mg once daily, increased to 60 mg once daily if insufficient relief
  • Dosage for Rheumatoid arthritis: 90 mg once daily
  • Dosage for Ankylosing spondylitis: 90 mg once daily
  • Dosage for Acute gouty arthritis: 120 mg once daily for 8 days
  • Dosage for Postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days

Interaction

  • Increased prothrombin time with oral anticoagulants
  • NSAIDs may reduce the effect of diuretics and other antihypertensive drugs
  • Can be used concomitantly with low-dose acetylsalicylic acid for cardiovascular prophylaxis

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or active GI bleeding
  • Patients who have experienced allergic-type reactions to NSAIDs
  • Pregnancy
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance < 30 ml/min
  • Inflammatory bowel disease
  • Congestive heart failure
  • Patients with hypertension not adequately controlled

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Appetite and weight change
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Mental acuity impaired
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Not known whether excreted in human milk
  • Must not breastfeed

Precautions & Warnings

  • Caution advised with treatment of patients at risk of developing GI complication with NSAIDs
  • Treatment of patients with significant risk factors for cardiovascular events only after careful consideration
  • Monitoring of renal function in patients at risk
  • Caution in patients with history of cardiac failure, left ventricular dysfunction, hypertension, and pre-existing edema
  • Monitoring of hepatic function tests, discontinuation at signs of hepatic insufficiency or hypersensitivity
  • May mask fever and other signs of inflammation, caution with co-administration with warfarin or other oral anticoagulants

Overdose Effects

  • Administration of single doses up to 500 mg and multiple doses up to 150 mg/day for 21 days did not result in significant toxicity
  • Usual supportive measures recommended in the event of overdose

Therapeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store at a temperature below 30°C, protect from light & moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg

Common Questions about Biocox 90 mg Tablet

  • Selective COX-2 inhibitor
  • Indicated for symptomatic relief of Osteoarthritis (OA), Rheumatoid arthritis (RA), Ankylosing spondylitis
  • Duration of effect: 20-24 hours
  • Onset of action: Within 1-2 hours, faster if taken without food
  • Pregnancy warnings, not habit forming, not recommended for breastfeeding
  • Not safe with alcohol, may affect alertness, caution in patients with kidney and liver disease
  • Quick Tips: Helps relieve pain and inflammation, may cause fewer stomach problems, may cause dizziness and fatigue

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