Etonil 60 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Etoricoxib |
Company | Pharmasia limited |
Also available as |
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Symptomatic relief of Rheumatoid arthritis (RA)
- Symptomatic relief of Ankylosing spondylitis
- Symptomatic relief of acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation
- Primarily responsible for the synthesis of prostanoid mediators of pain, inflammation, and fever
Dosage & Administration
- Recommended dose for Osteoarthritis: 30 mg once daily
- Recommended dose for Rheumatoid arthritis: 90 mg once daily
- Recommended dose for Ankylosing spondylitis: 90 mg once daily
- Recommended dose for Acute gouty arthritis: 120 mg once daily for 8 days
- Recommended dose for Postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days
- Shortest duration and lowest effective daily dose should be used
- The patient's need for symptomatic relief and response to therapy should be re-evaluated periodically
Drug Interaction
- Potential interaction with Oral anticoagulants, Diuretics, ACE inhibitors, Angiotensin II Antagonists, Acetylsalicylic Acid, Ciclosporin, Tacrolimus, Lithium
- Take without regard to meals
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Active peptic ulceration or active gastrointestinal (GI) bleeding
- Patients with bronchospasm, acute rhinitis, nasal polyps, angioneurotic edema, urticaria, or allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 inhibitors
- Pregnancy and lactation
- Severe hepatic dysfunction (serum albumin <25 g/l or Child-Pugh score 10)
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure, Hypertension, Ischaemic heart disease, Peripheral arterial disease, or Cerebrovascular disease
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Not known whether excreted in human milk
- Excreted in the milk of lactating rats
Precautions & Warnings
- Caution advised with treatment of patients most at risk of developing a GI complication with NSAIDs
- Patients with significant risk factors for cardiovascular events should only be treated after careful consideration
- Administration of the medicine may cause a reduction in prostaglandin formation and impair renal function
- Caution should be exercised in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension
- Patients with symptoms and/or signs suggesting liver dysfunction should be monitored
- Discontinue medicine at the first appearance of skin rash, mucosal lesions, or any other sign of hypersensitivity
- May mask fever and other signs of inflammation
- Caution should be exercised when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
- Usual supportive measures should be employed in the event of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
Common Questions
- What is Etonil 60 mg Tablet?
- What are the uses of Etonil 60 mg Tablet?
- How long is the duration of effect of Etonil 60 mg Tablet?
- What is the onset of action of Etonil 60 mg Tablet?
- Are there any pregnancy warnings of Etonil 60 mg Tablet?
- Is it habit forming of Etonil 60 mg Tablet?
- Are there any breast-feeding warnings of Etonil 60 mg Tablet?
- Is Etonil 60 mg Tablet safe with alcohol?
- Is Etonil 60 mg Tablet safe to drive while on this medicine?
- Does Etonil 60 mg Tablet affect kidney function?
- Does Etonil 60 mg Tablet affect liver function
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