Etonov 60 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Novus pharmaceuticals ltd |
| Also available as |
Title
Etonov 60 mg Tablet
Categories
- Pain Relief
- Arthritis
- Inflammation
- NSAIDs
Description
Etonov 60 mg Tablet is a potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor for the symptomatic relief of Osteoarthritis (OA), Rheumatoid arthritis (RA), Ankylosing spondylitis, the pain and signs of inflammation associated with acute gouty arthritis, and for the short-term treatment of moderate pain associated with dental surgery.
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Symptomatic relief of Rheumatoid arthritis (RA)
- Symptomatic relief of Ankylosing spondylitis
- Symptomatic relief of acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
Etoricoxib is a potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor within, and significantly above, the clinical dose range. Selective inhibition of COX-2 by etoricoxib decreases signs and symptoms of pain, inflammation, and fever with decreased potential for GI toxicity and effects on platelet aggregation.
Dosage
- Osteoarthritis: 30 mg once daily, may increase to 60 mg once daily if needed
- Rheumatoid arthritis: 90 mg once daily
- Ankylosing spondylitis: 90 mg once daily
- Acute gouty arthritis: 120 mg once daily for 8 days
- Postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days
Interaction with medicine
- Oral anticoagulants: Increase in prothrombin time
- Diuretics, ACE inhibitors, Angiotensin II Antagonists: May reduce the effect
- Acetylsalicylic Acid: Can be used concomitantly at low doses for cardiovascular prophylaxis
- Ciclosporin and tacrolimus: May increase the nephrotoxic effect
- Lithium: Decreases lithium renal excretion and increases lithium plasma levels
Interaction with food others
Take without regards to meals
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active GI bleeding
- Patients who have experienced allergic-type reactions after taking NSAIDs including COX-2 inhibitors
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Hypertension not adequately controlled
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Change in appetite and weight
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy lactation
Not recommended in women attempting to conceive. Not known if excreted in human milk. Women must not breastfeed while using Etoricoxib.
Precautions warnings
- Caution in patients at risk of GI complications with NSAIDs
- Caution in patients with significant risk factors for cardiovascular events
- Monitoring of renal function in patients with reduced renal blood flow
- Caution in patients with cardiac failure, left ventricular dysfunction, hypertension, pre-existing edema
- Monitoring of liver function; discontinue at signs of hepatic insufficiency
- Discontinue at first appearance of hypersensitivity
- May mask fever and other signs of inflammation
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose effects
Single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity. Employ usual supportive measures in case of overdose.
Therapeutic class
Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage conditions
Store at a temperature below 30°C, protect from light and moisture. Keep out of reach of children.
Chemical structure
- Molecular Formula: C18H15ClN2O2S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg
Commonly asked questions
- What is Etonov 60 mg Tablet?
- What are the uses of Etonov 60 mg Tablet?
- Duration of effect of Etonov 60 mg Tablet
- Onset of action of Etonov 60 mg Tablet
- Pregnancy warnings of Etonov 60 mg Tablet
- Habit forming tendencies of Etonov 60 mg Tablet
- Breast-feeding warnings of Etonov 60 mg Tablet
- Safety with alcohol
- Safety to drive while on this medicine
- Effect on kidney function
- Effect on liver function
- Quick Tips