Etovan 120 mg (Tablet)
Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Aristopharma ltd |
| Also available as |
Product title
- Etovan 120 mg Tablet
Therapeutic class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Pharmacological action
- Potent orally active cyclooxygenase-2 (COX-2) specific inhibitor
Indications
- Relief of Osteoarthritis (OA)
- Relief of Rheumatoid arthritis (RA)
- Relief of Ankylosing spondylitis
- Relief of pain and signs of inflammation associated with acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Dosage and administration
- Recommended dose for Osteoarthritis: 30 mg once daily
- Recommended dose for Rheumatoid arthritis: 90 mg once daily
- Recommended dose for Ankylosing spondylitis: 90 mg once daily
- Recommended dose for Acute gouty arthritis: 120 mg once daily for 8 days
- Recommended dose for Postoperative dental surgery pain: 90 mg once daily for maximum 3 days
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active gastro-intestinal (GI) bleeding
- Patients with bronchospasm, nasal polyps or allergic reactions to acetylsalicylic acid or NSAIDs
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure
- Patients with hypertension not adequately controlled
- Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Ecchymosis
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Appetite and weight change
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Mental acuity impaired
- Paraesthesia
- Electrolyte disturbance
- Myalgia and arthralgia
- Confusion
- Hallucinations
Pregnancy lactation
- Not recommended for women attempting to conceive
- Not recommended for lactating women
Precautions warnings
- Caution advised for patients at risk of developing gastrointestinal complications with NSAIDs
- Caution for patients with significant cardiovascular risk factors
- Monitoring of renal function recommended
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function recommended
- Discontinue at first appearance of hypersensitivity signs
- May mask fever and other signs of inflammation
- Exercise caution when co-administering with warfarin or other oral anticoagulants
Overdose effects
- No significant toxicity observed at single doses up to 500 mg
- Supportive measures recommended in case of overdose
Interaction with medications
- Increase in prothrombin time with chronic warfarin therapy
- Potential reduction in the effect of diuretics and other antihypertensive drugs
- Can be used concomitantly with acetylsalicylic acid at doses used for cardiovascular prophylaxis
- Potential nephrotoxic effect increase with ciclosporin or tacrolimus coadministration
- NSAIDs can decrease lithium renal excretion and increase lithium plasma levels
Interaction with food
- Take without regards to meals
Storage conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical structure
- Molecular Formula: C18H15ClN2O2S
Duration of effect
- Average duration of 20-24 hours
Onset of action
- Onset can be observed within 1-2 hours of administration
- Faster onset if taken without food
Pregnancy warnings
- Consult doctor before use by pregnant women
Habit forming tendencies
- No habit-forming tendencies reported
Breastfeeding warnings
- Not recommended for use by breastfeeding mothers
Safety with alcohol
- Unsafe to consume with alcohol
Effect on kidney function
- Caution in patients with kidney disease
- Strictly not recommended in patients with severe kidney disease
Effect on liver function
- Caution in patients with liver disease
- Strictly not recommended in patients with severe liver disease
Quick tips
- Helps relieve pain and inflammation
- May cause fewer stomach problems compared to other NSAIDs like Ibuprofen or Naproxen
- May cause dizziness and fatigue, avoid activities requiring concentration
- Avoid alcohol consumption
- Monitor blood pressure regularly, especially in the first two weeks
- Inform doctor of history of stomach ulcers, heart diseases, high blood pressure, liver or kidney disease
- Regular liver function monitoring during long-term treatment
- Not recommended during pregnancy, planning to conceive, or breastfeeding