Recox 120 mg (Tablet)
Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Renata limited |
| Also available as |
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Symptomatic relief of Rheumatoid arthritis (RA)
- Symptomatic relief of Ankylosing spondylitis
- Symptomatic relief of acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
Etoricoxib is a potent, orally active COX-2 specific inhibitor within the clinical dose range. It decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation.
Dosage & Administration
- Recommended doses for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gouty arthritis, and postoperative dental surgery pain
- Adolescents over 16 years: adult dosages apply
Interaction
- Interaction with oral anticoagulants
- Interaction with diuretics, ACE inhibitors, and Angiotensin II Antagonists
- Concomitant use with acetylsalicylic acid for cardiovascular prophylaxis
- Potential interaction with ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or GI bleeding
- History of allergic-type reactions after taking acetylsalicylic acid or NSAIDs
- Pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, inflammatory bowel disease, congestive heart failure, uncontrolled hypertension, established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
- Children and adolescents under 16 years of age
Side Effects
- Palpitation
- Fatigue
- Influenza-like symptoms
- Dry mouth
- Taste disturbance
- Mouth ulcer
- Atrial fibrillation
- Transient ischaemic attack
- Chest pain
- Flushing
- Cough
- Dyspnoea
- Epistaxis
- Anxiety
- Impaired mental acuity
- Paraesthesia
- Electrolyte disturbance
- Myalgia
- Arthralgia
- Confusion
- Hallucinations
Pregnancy & Lactation
Etoricoxib is not recommended in women attempting to conceive. It is excreted in the milk of lactating rats and must not be used during breastfeeding.
Precautions & Warnings
- Caution with patients at high risk of developing GI complications with NSAIDs
- Careful consideration for patients with significant risk factors for cardiovascular events
- Monitoring of renal function for patients with impaired renal function
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension
- Monitoring of liver function, discontinuation at signs of liver dysfunction, and hypersensitivity
- Potential impact on fever and inflammation signs when co-administered with warfarin or other oral anticoagulants
Overdose Effects
Up to 500 mg single dose and 150 mg/day for 21 days did not result in significant toxicity. Employ supportive measures in the event of overdose.
Therapeutic Class
Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Store at a temperature below 30°C, protect from light & moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg
Common Questions about Recox 120 mg Tablet
- What is Recox 120 mg Tablet?
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- Duration of effect of Recox 120 mg Tablet?
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- Safety with alcohol?
- Safety to drive while on this medicine?
- Impact on kidney function?
- Impact on liver function?
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