Iben 400 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Ibuprofen |
Company | Zenith pharmaceuticals ltd |
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Gouty arthritis
- Juvenile polyarthritis
- Ankylosing spondylitis
- Synovitis
- Low back pain
- Dysmenorrhoea
- Fever
- Migraine
- Soft tissue injuries
- Pain & Inflammation in dental and musculoskeletal origin
Pharmacology
Ibuprofen has a high level of anti-inflammatory, anti-pyretic, and analgesic activity. The analgesic effects of Ibuprofen are due to both a peripheral and a central effect. Ibuprofen is a potent inhibitor of the enzyme cyclooxygenase, which thus results in a marked reduction in prostaglandin synthesis. Ibuprofen also inhibits the synthesis of some lipo-oxygenase products. Ibuprofen thus quickly relieves pain and stiffness, reduces swelling, and improves the movement of different joints of arthritis sufferers.
Dosage & Administration
- Oral dosage form:
- Adults: 400 mg 3 times daily. Max 2400 mg daily
- Children:
- 3-6 months: 30 mg/kg daily
- 6 months-1 year: 30 mg/kg daily
- 1-4 years: 30 mg/kg daily
- 4-7 years: 30 mg/kg daily
- 7-10 years: 30 mg/kg daily
- 10-12 years: 30 mg/kg daily
- Juvenile rheumatoid arthritis: 30-40 mg/kg of body weight daily
- Topical gel:
- Adults: 4 to 10cm on affected area. Max 4 times a day
- Use in children: Not recommended for use in children under 12 years
Contraindications
Hypersensitivity to Ibuprofen, Severe or active peptic ulceration
Side Effects
- Upset stomach
- Vomiting
- Heartburn
- Nausea
Pregnancy & Lactation
Adverse effects on the developing fetus cannot be fully excluded. Not recommended during pregnancy and for nursing mothers unless benefits outweigh risks
Precautions & Warnings
Use with caution in gastrointestinal hemorrhage or ulcer. Ocular monitoring for patients on long-term therapy. Caution in patients with asthma and history of hypersensitivity to other nonsteroidal anti-inflammatory agents
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Store in a cool and dry place, protected from light