Trufen 400 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ibuprofen |
| Company | Modern pharmaceuticals ltd |
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Gouty arthritis
- Juvenile polyarthritis
- Ankylosing spondylitis
- Synovitis
- Low back pain
- Dysmenorrhoea
- Fever
- Migraine
- Soft tissue injuries
- Pain & Inflammation in dental and musculoskeletal origin
Pharmacology
Ibuprofen has high levels of anti-inflammatory, anti-pyretic, and analgesic activity. It inhibits the enzyme cyclooxygenase, leading to a reduction in prostaglandin synthesis and some lipo-oxygenase products, providing relief from pain, stiffness, and swelling.
Dosage & Administration
Adult dosage: Initial dose of 400 mg 3 times daily. Pediatric dosage based on age and body weight. Topical gel application for adults involves squeezing 4 to 10cm of gel on the affected area, not to be repeated more frequently than every four hours and no more than four times a day.
Contraindications
Patients with previous hypersensitivity to Ibuprofen and those with severe or active peptic ulceration should avoid using this product.
Side Effects
Possible side effects include upset stomach, vomiting, heartburn, and nausea.
Pregnancy & Lactation
Ibuprofen should not be used during pregnancy and for nursing mothers unless the potential benefits outweigh the risks.
Precautions & Warnings
Caution should be exercised in patients with a history of gastrointestinal hemorrhage or ulcer, and long-term therapy requires ocular monitoring at regular intervals. Patients with systemic lupus erythematosus are more likely to develop hypersensitivity.
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Store in a cool and dry place, protected from light. Keep out of reach of children.