Atova 10 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title
Atova 10 mg Tablet
Categories
- Medicine
- Pharmaceutical
Description
Atova is indicated to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in various diseases. It is also a selective inhibitor of HMG-CoA reductase, with pharmacological, dosage, and administration information as well as interactions, contraindications, side effects, and precautions.
DosageForm
Tablet
DosageStrength
10 mg
Indications
- Reduction of elevated total cholesterol
- Reduction of LDL cholesterol
- Reduction of apolipoprotein B (Apo-B)
- Reduction of triglyceride levels
DiseasesIndicatedFor
- Heterozygous familial hypercholesterolaemia
- Homozygous familial hypercholesterolaemia
- Mixed dyslipidemia (Fredrickson Type Ia and Ib)
- Hypertriglyceridaemia (Fredrickson Type IV)
- Dysbetalipoproteinaemia (Fredrickson Type III)
- Patients with coronary artery disease
- Diabetes mellitus or renal transplantation patients
ModeOfAction
Selective inhibitor of HMG-CoA reductase, lowering plasma cholesterol and lipoprotein levels
Absorption
Rapidly absorbed after oral administration, with maximum plasma concentrations occurring within 1 to 2 hours
Distribution
Mean volume of distribution is approximately 381 liters, with 98% bound to plasma proteins
Metabolism
Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products
Excretion
Eliminated primarily in bile following hepatic and/or extra-hepatic metabolism, with a mean plasma elimination half-life of approximately 14 hours
Interactions
- Cyclosporine
- Fibric acid derivatives
- Niacin
- Erythromycin
- Azole antifungals
- Antacids
- Colestipol
- Digoxin
- Oral contraceptives
- Warfarin
Contraindications
- Hypersensitivity to any component
- Active liver disease or unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
SideEffects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
PregnancyAndLactation
- Contraindicated during pregnancy
- Not known if excreted in human milk
- Safety in pregnant and lactating women not established
PrecautionsAndWarnings
- Liver function tests should be performed before initiation of treatment
- Discontinue if markedly elevated CPK levels occur or myopathy is diagnosed or suspected
SpecialPopulations
- Geriatric
- Pediatric
- Gender
- Renal Insufficiency
- Hemodialysis
- Hepatic Insufficiency
OverdoseEffects
No specific treatment available, should be treated symptomatically and supportive measures instituted
TherapeuticClass
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
StorageConditions
Keep in a dry place away from light and heat, keep out of the reach of children
ChemicalStructure
- MolecularFormula: C33H35FN2O5
- ChemicalStructureImageURL: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg
CommonlyAskedQuestions
- What is Atova 10 mg Tablet?
- How should I take Atova 10 mg Tablet?
- What are the uses of Atova 10 mg Tablet?
- What are the side effects of Atova 10 mg Tablet?
- What are the instructions for storage and disposal of Atova 10 mg Tablet?
- Is Atova 10 mg Tablet used for lowering cholesterol?
- Will taking Atova 10 mg Tablet increase my risk of diabetes?
- For how long do I need to take Atova 10 mg Tablet? Is it safe for long-term use?
- Does Atova 10 mg Tablet cause weight loss?
- Can I stop taking Atova 10 mg Tablet?
- Does Atova 10 mg Tablet cause memory loss?
- Does Atova 10 mg Tablet make you tired?
- Can Atova 10 mg Tablet be prescribed to children?
- Is Atova 10 mg Tablet a blood thinner?
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