Kynol TR 200 mg (Capsule (Timed Release))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Ketoprofen oral injection
Company Eskayef pharmaceuticals ltd

Title and Categories

  • Ketoprofen Medicine
  • Pain Relief
  • Anti-inflammatory Drug
  • NSAID

Dimensions and Size Options

    Color Options

      Functions

      • Anti-inflammatory
      • Analgesic
      • Antipyretic

      Materials

        Technical Specifications

        • Rapid and almost complete absorption from the GI tract
        • Approximately 99% bound to plasma protein, mainly albumin
        • Metabolized in the liver via conjugation with glucuronic acid
        • Excretion in urine and feces
        • Elimination half-life of approximately 1.1-4 hours

        Design Elements

          Usability Features

          • Oral forms should be taken with fluids, preferably with food

          Dosage Information

          • Starting dose of 150 to 300 mg/day in 3 divided doses
          • Maintenance dosage of usually 100 to 200 mg/day
          • Maximum daily dose of 300 mg
          • Usual recommended dose for pain and dysmenorrhea is 25 to 50 mg every 6 to 8 hours
          • Total daily dose should not exceed 300 mg

          Interaction

          • Not recommended drug associations with other NSAIDs and high dose salicylates
          • Increased risk of bleeding when coadministered with anticoagulants
          • Risk of elevation of lithium plasma levels when coadministered with lithium
          • Increased risk of haematologic toxicity of methotrexate at higher doses
          • Enhanced risk of hyperkalemia when coadministered with certain medicinal products

          Contraindications

          • History of hypersensitivity reactions to ketoprofen, ASA, or other NSAIDs
          • Severe heart failure
          • Active or history of peptic ulcer/hemorrhage
          • Severe hepatic or renal insufficiency
          • Third trimester of pregnancy
          • Rectitis or history of proctorrhagia

          Side Effects

          • Hematological disorders
          • Immune system reactions
          • Nervous system disorders
          • Cardiac and vascular disorders
          • Respiratory and gastrointestinal disorders
          • Hepatobiliary and skin disorders
          • Metabolic and urinary disorders

          Pregnancy & Lactation

          • Avoid use during the first and second trimester
          • Contraindicated in the third trimester
          • Not recommended for nursing mothers

          Precautions & Warnings

          • Given with care to patients with a history of gastrointestinal disease
          • Careful monitoring of renal function in certain patients
          • Caution in patients with hypertension or congestive heart failure
          • Increased risk of atrial fibrillation
          • Potassium levels must be monitored in certain patients
          • Masking of infection signs
          • Evaluation of liver function tests periodically
          • Impairment of female fertility
          • Not recommended in women attempting to conceive

          Use in Special Populations

          • Reduced initial dosage for the elderly
          • Careful monitoring and minimal effective dosage for hepatic impairment and renal impairment

          Overdose Effects

          • Symptoms limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain
          • No specific antidotes
          • Recommendation for gastric lavage and supportive treatment
          • Possible use of hemodialysis in renal failure

          Therapeutic Class

          • Drugs for Osteoarthritis
          • Drugs used for Rheumatoid Arthritis
          • NSAIDs

          Storage Conditions

          • Protect from light
          • Store below 30°C
          • Do not use later than the date of expiry
          • Keep out of the reach of children
          • Dispensed only on the prescription of a registered physician

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