Profenid-E 100 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.03 (5 x 10: ৳ 451.50)
Strip Price: ৳ 90.30

Medicine Details

Category Details
Generic Ketoprofen oral injection
Company Synovia pharma plc
Also available as
Profenid e 50 mg tablet Profenid 100 mg injection Profenid cr 100 mg capsule Profenid cr 200 mg capsule

Indications

  • Rheumatoid arthritis
  • Degenerative joint diseases
  • Musculoskeletal and joint disorders
  • Pain relief

Pharmacology

  • Non-steroidal anti-inflammatory drug
  • Analgesic
  • Antipyretic
  • Prostaglandin synthesis inhibition
  • Lysosomal membrane stabilization
  • Leukotriene synthesis inhibition

Dosage

  • Anti-inflammatory dosage
  • Management of pain and dysmenorrhea
  • Starting dose
  • Maintenance dosage
  • Maximum daily dose
  • Twice daily dose regimen
  • Oral administration with fluids

Interaction

  • Not recommended drug associations
  • Increased risk of bleeding
  • Medicinal products promoting hyperkalemia
  • Increased risk of gastrointestinal ulceration or bleeding
  • Nephrotoxicity risk

Contraindications

  • Hypersensitivity reactions
  • Severe heart failure
  • Peptic ulcer/hemorrhage
  • Severe hepatic or renal insufficiency
  • Third trimester of pregnancy
  • Rectitis or proctorrhagia

Side Effects

  • Haemorrhagic anaemia
  • Agranulocytosis
  • Thrombocytopenia
  • Dizziness
  • Nausea
  • Asthma
  • Hepatitis
  • Rash
  • Hyponatremia
  • Weight increased

Pregnancy & Lactation

  • Avoidance during first and second trimester
  • Contraindicated in the last trimester
  • Not recommended in nursing mothers

Precautions & Warnings

  • Caution in patients with gastrointestinal disease
  • Monitoring of renal function and transaminase levels
  • Potential fluid retention and oedema
  • Hyperkalemia risk
  • Masking of signs of infection progression
  • Visual disturbances monitoring
  • Impaired female fertility

Use in Special Populations

  • Recommended initial dosage reduction for elderly
  • Monitoring and minimal effective dosage for hepatic impairment
  • Recommended initial dosage reduction for renal impairment

Overdose Effects

  • Symptoms of overdose
  • No specific antidotes
  • Recommended gastric lavage
  • Supportive treatment
  • Hemodialysis for renal failure

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Protect from light
  • Store below 30°C
  • Do not use after expiry date
  • Keep out of reach of children
  • Dispensed only on prescription

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