Profenid 2.5% w/w (Gel)

Title

• Ketoprofen Gel

Categories

• Pain Relief
• Topical Medication
• Non-steroidal Anti-inflammatory Drug

Description

• Symptomatic treatment of mild to moderate local pain associated with muscle and/or joint injuries
• Contains Ketoprofen - a non-steroidal anti-inflammatory drug (NSAID)

Ingredients

• Ketoprofen

DosageForm

• Gel

Indications

• For symptomatic treatment of mild to moderate local pain associated with muscle and/or joint injuries
• E.g. sports injuries

Pharmacology

• Non-steroidal anti-inflammatory drug (NSAID)
• Analgesic and antipyretic actions
• Inhibition of prostaglandin synthesis
• Stabilizes lysosomal membranes
• Inhibits leukotriene synthesis
• Antibradykinin activity

DosageAndAdministration

• Applied 2-3 times daily on painful or inflamed area
• Maximum daily dose of 15 grams
• Length of treatment should not exceed one week
• To be massaged onto the skin for a few minutes

Interaction

• Unlikely interaction due to low serum concentrations following topical administration

Contraindications

• Known hypersensitivity to Ketoprofen, fenofibrate, tiaprofenic acid, acetylsalicylic acid, or other NSAIDs
• Photosensitivity reactions
• Cutaneous reactions to certain substances
• Pathological skin changes such as eczema or acne
• Infected skin or open wounds
• Sun exposure during treatment and 2 weeks after discontinuation

SideEffects

• Immune system disorders: Anaphylactic shock, angioedema, hypersensitivity reactions
• Gastrointestinal disorders: Nausea, abdominal pain, vomiting, flatulence
• Skin and subcutaneous tissue disorders: Erythema, pruritus, photosensitivity reactions, dermatitis bullous, urticaria
• Renal and urinary disorders: Worsening renal insufficiency

PregnancyAndLactation

• Avoid use during the first and second trimester of pregnancy
• Potential fetal toxicity in the third trimester
• Not recommended in nursing mothers

PrecautionsAndWarnings

• Use with caution in patients with reduced heart, liver or renal function
• Avoid use with occlusive dressings
• Avoid contact with mucous membranes of the eyes
• Risk of serious skin reactions like Stevens-Johnson Syndrome
• Protect treated region with clothing when outdoor
• Carry out prolonged hand washing after each use

OverdoseEffects

• Unlikely overdose with topical administration
• Symptomatic and supportive treatment if accidentally ingested

TherapeuticClass

• Non-steroidal Anti-inflammatory Drugs (NSAIDs)

StorageConditions

• Store below 25°C
• Close tube after use
• Keep out of reach of children
• Do not use after expiry date
• Dispensed only on a registered physician's prescription

Related Brands

• Festam 2.5% w/w (Gel) - pacific-pharmaceuticals-ltd