Top 50 mg (Tablet (Enteric Coated))
Unit Price: ৳ 3.51 (5 x 10: ৳ 175.42)
Strip Price: ৳ 35.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketoprofen oral injection |
| Company | Biopharma limited |
| Also available as |
Indications
- Rheumatoid arthritis
- Degenerative joint diseases
- Musculoskeletal and joint disorders
- Pain management
Pharmacology
- NSAID
- Analgesic
- Antipyretic
- Inhibition of prostaglandin synthesis
- Lysosomal membrane stabilization
- Metabolism in liver
- Plasma protein binding
- Elimination half-life
- Urinary and fecal excretion
- Peak concentration after IM injection
- Metabolism via conjugation
Dosage
- Anti-inflammatory dosage
- Management of pain and dysmenorrhea
- Recommended starting dose
- Maintenance dosage
- Maximum daily dose
- Usual recommended dose
- Frequency of administration
Administration
- Oral administration
- Administration with fluids
- Preferably with food
Interaction
- Not recommended drug associations
- Increased risk of gastrointestinal ulceration and bleeding
- Coadministration precautions
- Effects on lithium levels
- Interaction with methotrexate
- Drug associations promoting hyperkalemia
- Corticosteroids interaction
- Diuretics interaction
- ACE inhibitors and Angiotensin II Antagonists interaction
- Interaction with nicorandil
- Cardiac glycosides interaction
- Cyclosporin interaction
- Tenofovir interaction
- Antihypertensive agents interaction
- Thrombolytics interaction
- Probenecid interaction
- Selective serotonin reuptake inhibitors (SSRIs) interaction
Contraindications
- Hypersensitivity reactions
- Severe heart failure
- Peptic ulcer/hemorrhage
- History of gastrointestinal bleeding
- Severe hepatic insufficiency
- Severe renal insufficiency
- Third trimester of pregnancy
- Rectitis or history of proctorrhagia
Side Effects
- Hematologic disorders
- Immune system reactions
- Nervous system effects
- Vision and hearing disorders
- Cardiac and vascular effects
- Respiratory and thoracic effects
- Gastrointestinal effects
- Hepatobiliary effects
- Skin and subcutaneous reactions
- Renal and urinary effects
- General disorder and administration site conditions
- Metabolism and nutritional disorders
Pregnancy & Lactation
- Use during first and second trimester
- Contraindicated during last trimester
- Not recommended for nursing mothers
Precautions & Warnings
- Gastrointestinal disease precautions
- Renal function monitoring
- Fluid retention and edema precautions
- Atrial fibrillation risk
- Hyperkalemia precautions
- Masking of infection progression
- Liver function tests evaluation
- Visual disturbances precautions
- Female fertility impairment
- Special considerations for elderly, hepatic impairment, and renal impairment
Use in Special Populations
- Elderly use recommendation
- Hepatic impairment caution
- Renal impairment caution
Overdose Effects
- Reported overdose cases
- Symptoms of overdose
- Gastric lavage recommendation
- Symptomatic and supportive treatment
- Hemodialysis in case of renal failure
Therapeutic Class
- Osteoarthritis drugs
- Rheumatoid Arthritis drugs
- NSAIDs
Storage Conditions
- Light protection
- Temperature storage
- Expiry date
- Child-proof storage
- Prescription requirement