Top 100 mg (Tablet (Enteric Coated))
Unit Price: ৳ 6.02 (3 x 10: ৳ 180.50)
Strip Price: ৳ 60.17
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketoprofen oral injection |
| Company | Biopharma limited |
| Also available as |
Indications
- Rheumatoid arthritis
- Degenerative joint diseases
- Musculoskeletal and joint disorders
- Pain relief
- Dental pain
- Headache
- Dysmenorrhea
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Analgesic actions
- Antipyretic actions
- Prostaglandin synthesis inhibition
- Lysosomal membrane stabilization
- Leukotriene synthesis inhibition
- Antibradykinin activity
- Central nervous system (CNS) effect
- Absorption rate
- Plasma protein binding
- Metabolism in the liver
- Urinary excretion
- IM injection kinetics
- Elimination half-life
Dosage
- Anti-inflammatory dosage recommendation
- Pain management dosage recommendation
- Administration with fluids
- Precautions for food intake
Interaction
- Non-recommended drug associations
- Close monitoring of specific drug coadministration
- Risk of elevation of lithium plasma levels
- Increased risk of haematologic toxicity
- Medicinal products promoting hyperkalemia
- Increased risk of gastrointestinal ulceration or bleeding
- Risk of renal failure
- Risk of decreased antihypertensive potency
- Risk of bleeding
- Marked reduction of plasma clearance
Contraindications
- Hypersensitivity reactions
- Severe heart failure
- Active or history of peptic ulcer/hemorrhage
- History of gastrointestinal bleeding or perforation
- Severe hepatic insufficiency
- Severe renal insufficiency
- Third trimester of pregnancy
- Rectitis or history of proctorrhagia
Side Effects
- Blood and lymphatic system disorders
- Immune system disorders
- Nervous system disorders
- Eye disorders
- Ear and labyrinth disorders
- Cardiac disorders
- Vascular disorders
- Respiratory, thoracic and mediastinal disorders
- Gastrointestinal disorders
- Hepatobiliary disorders
- Skin and subcutaneous disorders
- Renal and urinary disorders
- General disorders and administration site conditions
- Metabolism and nutritional disorders
- Investigations
Pregnancy & Lactation
- Contraindication in third trimester
- Avoidance during first and second trimester
- Not recommended in nursing mothers
Precautions & Warnings
- Gastrointestinal disease caution
- Renal function monitoring
- Care in heart failure and cirrhosis
- Increased risk of atrial fibrillation
- Potential for hyperkalemia
- Masking signs of infection progression
- Liver function evaluation
- Visual disturbances caution
- Impact on female fertility
Use in Special Populations
- Elderly dosage adjustment
- Hepatic impairment monitoring
- Renal impairment dosage adjustment
Overdose Effects
- Reported cases
- Symptoms observed
- Lethargy
- Nausea and vomiting
- Supportive treatment recommendation
- Gastric lavage in overdose cases
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Protection from light
- Temperature storage limit
- Expiry date adherence
- Keep out of reach of children
- Prescription dispensing requirement