Amifen 50 mg/5 ml (Oral Suspension)

Indications

• Fever
• Toothache
• Headache
• Migraine
• Primary dysmenorrhoea
• Menorrhagia
• Mild to moderate pain in rheumatoid arthritis and osteoarthritis
• Traumatic pain
• Low-back pain
• Juvenile chronic arthritis in children

Pharmacology

• Demonstrated analgesic activity
• Anti-inflammatory activity
• Antipyretic activity
• Dual action on prostaglandins
• Inhibition of prostaglandin synthetase
• Antagonizes actions of prostaglandin at receptor sites

Dosage & Administration

• Adult dosage: 500 mg three times per day with meals
• Reduced adult dosage: 250 mg three times daily
• Menorrhagia dosage: 500 mg three times daily from the onset of menses
• Children dosage: varies based on age
• Treatment not to be continued for more than 7 days without physician's advice

Interaction

• Concomitant administration of Amifen and Aspirin not recommended
• Potential increased adverse effects with concomitant administration of Amifen and Aspirin
• Inhibition of platelet aggregation with concomitant administration of Amifen and warfarin
• Prolongation of prothrombin time in patients on warfarin therapy with Amifen

Contraindications

• Known hypersensitivity to Mefenamic Acid
• Peptic ulcer
• Inflammatory bowel diseases
• Hepatic or renal impairment
• Symptoms of bronchospasm induced by aspirin and/or other NSAID's
• Symptoms of skin rashes induced by aspirin and/or other NSAID's

Side Effects

• Gastrointestinal adverse experiences
• Abdominal pain
• Constipation
• Diarrhoea
• Dyspepsia
• Flatulence
• Nausea
• Gastric ulcers
• Vomiting
• Dizziness
• Abnormal renal function
• Pruritus
• Rashes

Pregnancy & Lactation

• Safety not established on reproductive capacity and pregnancy
• Use in women of childbearing potential and during pregnancy only when benefits outweigh risks
• Presence in breast milk and transmission to nursing infant
• Should not be taken by nursing mother

Precautions & Warnings

• Administer with caution in allergic diseases
• Administer with caution in asthma
• Withdraw treatment in case of diarrhoea
• Withdraw treatment in case of rashes
• Withdraw treatment in case of cholestatic jaundice
• Withdraw treatment in case of thrombocytopenia
• Withdraw treatment in case of haemolytic anaemia

Therapeutic Class

• Drugs for Osteoarthritis
• Drugs for Rheumatoid Arthritis
• Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

• Keep away from light
• Store in a cool and dry place
• Keep out of reach of children

Related Brands

• Amifen 500 mg (Tablet) - opsonin-pharma-ltd