Anaflex 250 mg (Tablet)

Unit Price: ৳ 9.00 (5 x 10: ৳ 450.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Naproxen sodium
Company Aci limited
Also available as
Anaflex 500 mg tablet Anaflex sr 500 mg tablet Anaflex 10 w gel

Title

  • Anaflex

Categories

  • Pain Relief
  • NSAIDs
  • Arthritis Medication

Description

  • Anaflex is indicated for the relief of symptoms of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, tendonitis, bursitis, acute gout, and primary dysmenorrhea & pain. It blocks COX-1 and COX-2 enzymes leading to decreased prostaglandin synthesis. It is available in enteric coated tablets, suspension, and gel forms. It interacts with ACE inhibitors, antacids, aspirin, diuretics, methotrexate, warfarin, and selective serotonin reuptake inhibitors (SSRI). It is contraindicated in patients with known hypersensitivity to naproxen and for perioperative pain in coronary artery bypass graft (CABG) surgery. Common side effects include gastrointestinal discomfort, central nervous system effects, dermatological effects, cardiovascular effects, visual and hearing disturbances. Its use during pregnancy and lactation requires careful consideration. Long-term administration may have renal and hepatic effects. It belongs to the therapeutic class of drugs for osteoarthritis, drugs used for rheumatoid arthritis, and non-steroidal anti-inflammatory drugs (NSAIDs). It should be stored below 30°C, protected from light & moisture, and out of reach of children.

Dimensions

  • Tablet form, suspension, gel

Color Options

  • N/A

Functions

  • Relieves symptoms of various types of arthritis
  • Manages dysmenorrhea & pain
  • Blocks COX-1 and COX-2 enzymes
  • Interacts with other medications
  • Exerts renal and hepatic effects

Materials

  • N/A

Technical Specifications

  • Enteric coated tablet: adult dosage for various indications
  • Enteric coated tablet: dosage for acute gout
  • Enteric coated tablet: dosage for dysmenorrhoea
  • Enteric coated tablet: dosage for other indications like analgesia and musculoskeletal disorders
  • Suspension dosage for juvenile rheumatoid arthritis
  • Dosage guide for naproxen suspension based on body weight
  • Recommended usage of naproxen gel

Design Elements

  • Enteric coated tablets
  • Suspension
  • Gel

Usability Features

  • Oral administration with water
  • Dosage preferably after meals
  • Storage conditions recommendation

Interaction

  • Diminishes the antihypertensive effect of ACE inhibitors
  • Delays the absorption of Anaflex with antacids & sucralfate
  • Increases adverse effects with aspirin
  • Reduces the natriuretic effect of diuretics
  • Enhances the toxicity of methotrexate
  • Increases the risk of GI bleeding with warfarin and selective serotonin reuptake inhibitors (SSRI)

Contraindications

  • Known hypersensitivity to Naproxen
  • Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  • Treatment of perioperative pain in coronary artery bypass graft (CABG) surgery

Side Effects

  • Gastrointestinal discomfort: heartburn, abdominal pain, nausea, diarrhea, dyspepsia
  • Central nervous system effects: headache, vertigo, drowsiness
  • Dermatological effects: pruritus (itching), purpura
  • Cardiovascular effects: edema, palpitation
  • Other effects: visual disturbances, hearing disturbances

Pregnancy & Lactation

  • Adverse effects on the fetus through pharmacological properties
  • Delay in parturition in animals and associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants
  • Excretion in small amounts in breast milk for nursing mothers
  • Considerations for use in the first and third trimesters
  • Balancing of benefits to the mother against possible risks to the fetus
  • Recommendations regarding breastfeeding during therapy

Precautions & Warnings

  • Renal effects including reports of abnormal renal pathology
  • Acute interstitial nephritis, hematuria, proteinuria, and occasionally nephrotic syndrome associated with Anaflex-containing products
  • Use with caution in patients with significantly impaired renal function
  • Monitoring of serum creatinine and/or creatinine clearance
  • Caution in patients with creatinine clearance of less than 20ml/min
  • Hepatic effects including moderate to severe jaundice attributed to Anaflex

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature: below 30°C
  • Protection from light & moisture
  • Keep out of reach of children

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