Anaflex 10% w/w (Gel)

15 gm tube: ৳ 80.00

Medicine Details

Indications

  • rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • juvenile arthritis
  • tendonitis
  • bursitis
  • acute gout
  • dysmenorrhea

Pharmacology

  • COX-1 and COX-2 enzyme inhibition
  • prostaglandin synthesis
  • antipyretic effects
  • analgesic effects
  • anti-inflammatory properties

Dosage & Administration

  • oral administration
  • enteric-coated tablets
  • suspension
  • gel
  • dose for different conditions
  • dose for adults
  • dose for children
  • dosage frequency
  • dosage intervals

Interaction

  • interaction with ACE inhibitors
  • interaction with antacids & sucralfate
  • interaction with aspirin
  • interaction with diuretics
  • interaction with methotrexate
  • interaction with warfarin
  • interaction with selective serotonin reuptake inhibitors (SSRI)

Contraindications

  • known hypersensitivity to naproxen
  • hypersensitivity to aspirin or other NSAIDs
  • perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • gastrointestinal side effects
  • central nervous system side effects
  • dermatological side effects
  • cardiovascular side effects
  • other reported side effects

Pregnancy & Lactation

  • adverse effects on the fetus
  • delay in parturition
  • premature closure of ductus arteriosus
  • severe pulmonary hypertension in infants
  • excretion in breast milk
  • risk balancing for the mother and fetus
  • breastfeeding precautions

Precautions & Warnings

  • renal effects
  • abnormal renal pathology
  • acute interstitial nephritis
  • hematuria
  • proteinuria
  • nephrotic syndrome
  • elimination by the kidneys
  • caution in patients with impaired renal function
  • hepatic effects
  • jaundice

Therapeutic Class

  • drugs for osteoarthritis
  • drugs for rheumatoid arthritis
  • non-steroidal anti-inflammatory drugs (NSAIDs)

Storage Conditions

  • temperature
  • protection from light
  • protection from moisture
  • keep out of the reach of children

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