Bpxen 500 mg (Tablet)

Unit Price: ৳ 7.50 (30's pack: ৳ 225.00)

Medicine Details

Category Details
Generic Naproxen sodium
Company Bristol pharmaceuticals ltd
Also available as

Indications

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Juvenile arthritis
  • Tendonitis
  • Bursitis
  • Acute gout
  • Primary dysmenorrhea

Pharmacology

  • COX-1 and COX-2 enzyme blocking
  • Prostaglandin synthesis inhibition
  • Antipyretic properties
  • Analgesic properties
  • Anti-inflammatory properties
  • Gastrointestinal upset linked to COX-1 enzyme
  • Renal toxicities linked to COX-1 enzyme

Dosage & Administration

  • Enteric coated tablets
  • Oral preparations
  • Naproxen Suspension
  • Naproxen Gel
  • Different doses for different indications
  • Dosage for adults
  • Dosage for children
  • Dosage frequency

Interaction

  • ACE inhibitors interaction
  • Antacids & Sucralfate interaction
  • Aspirin interaction
  • Diuretics interaction
  • Methotrexate interaction
  • Warfarin interaction
  • Selective Serotonin Reuptake Inhibitors (SSRI) interaction

Contraindications

  • Hypersensitivity to Naproxen
  • Asthma or allergic-type reactions after taking aspirin or other NSAIDs
  • Perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • Gastrointestinal side effects
  • Central Nervous System side effects
  • Dermatological side effects
  • Cardiovascular side effects
  • Other reported side effects

Pregnancy & Lactation

  • Adverse effects on fetus
  • Delay in parturition
  • Premature closure of ductus arteriosus
  • Severe pulmonary hypertension in infants
  • Excretion in breast milk
  • Balancing benefits to mother and risks to fetus

Precautions & Warnings

  • Renal effects
  • Nephrotoxicity
  • Acute interstitial nephritis
  • Proteinuria
  • Hepatic effects
  • Jaundice
  • Caution with impaired renal function
  • Monitoring of serum creatinine
  • Monitoring of creatinine clearance

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature requirements
  • Protection from light
  • Protection from moisture
  • Keep out of reach of children

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