Gloxen 250 mg (Tablet)

Unit Price: ৳ 4.00 (3 x 10: ৳ 120.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Naproxen sodium
Company Globe pharmaceuticals ltd
Also available as

Indications

  • Relief of rheumatoid arthritis symptoms
  • Relief of osteoarthritis symptoms
  • Relief of ankylosing spondylitis symptoms
  • Relief of juvenile arthritis symptoms
  • Relief of tendonitis symptoms
  • Relief of bursitis symptoms
  • Relief of acute gout symptoms
  • Management of primary dysmenorrhea & pain

Pharmacology

  • Blocks COX-1 and COX-2 enzymes
  • Decreases prostaglandin synthesis
  • Exerts antipyretic, analgesic and anti-inflammatory properties

Dosage & Administration

  • Oral intake with water after meals
  • Different dosage for adults and children
  • Available in enteric coated tablets, suspension, and gel form

Interaction

  • Interacts with ACE inhibitors
  • Interacts with antacids and sucralfate
  • Interacts with aspirin
  • Interacts with diuretics
  • Interacts with methotrexate
  • Interacts with Warfarin
  • Interacts with Selective Serotonin Reuptake Inhibitors (SSRI)

Contraindications

  • Hypersensitivity to Naproxen
  • Contraindicated for patients with asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  • Contraindicated for treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • Gastrointestinal side effects: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
  • Central Nervous System side effects: Headache, vertigo, drowsiness
  • Dermatological side effects: Pruritus (itching), purpura
  • Cardiovascular side effects: Edema, palpitation
  • Other side effects: Visual disturbances, hearing disturbances

Pregnancy & Lactation

  • May have adverse effects on the fetus
  • Causes a delay in parturition in animals
  • Associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants born to mothers taking Naproxen
  • Excreted in small amounts in the breast milk for nursing mothers

Precautions & Warnings

  • Renal effects: May result in renal papillary necrosis and other abnormal renal pathology
  • Renal effects: Reports of acute interstitial nephritis, hematuria, proteinuria, and occasionally nephrotic syndrome
  • Renal effects: Caution in patients with impaired renal function
  • Hepatic effects: Reports of moderate to severe jaundice

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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