Gloxen 500 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 6: ৳ 210.00)
Strip Price: ৳ 42.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Relief of rheumatoid arthritis
- Relief of osteoarthritis
- Relief of ankylosing spondylitis
- Relief of juvenile arthritis
- Relief of tendonitis
- Relief of bursitis
- Relief of acute gout
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreases prostaglandin synthesis
- Unique functional differences between COX-1 and COX-2 enzymes
Dosage & Administration
- Oral administration with water
- Dosage for adults with rheumatoid arthritis/osteoarthritis/ankylosing spondylitis
- Dosage for acute gout
- Dosage for dysmenorrhoea
- Dosage for other indications like analgesia and acute musculoskeletal disorders
- Dosage for children with juvenile rheumatoid arthritis
- Dosage for children based on weight
- Application frequency for gel
Interaction
- Diminishes the antihypertensive effect of ACE inhibitors
- Delays absorption with antacids & Sucralfate
- Increases adverse effects with Aspirin
- Reduces the natriuretic effect of Diuretics
- Enhances the toxicity of Methotrexate
- Increases the risk of GI bleeding with Warfarin
- Increases the risk of GI bleeding with Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System: Headache, vertigo, drowsiness
- Dermatological: Pruritus (itching), purpura
- Cardiovascular: Edema, palpitation
- Others: Visual disturbances, hearing disturbances
Pregnancy & Lactation
- May have adverse effects on the fetus
- Causes a delay in parturition in animals
- Associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants
- Excreted in small amounts in breast milk
Precautions & Warnings
- Renal effects: Possible renal pathology, acute interstitial nephritis, hematuria, proteinuria, and nephrotic syndrome
- Hepatic effects: Reports of moderate to severe jaundice
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children