Napro 250 mg (Tablet)

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Naproxen sodium
Company Aristopharma ltd
Also available as

Title

  • Napro

Categories

  • Medicine
  • Pain Relief
  • Anti-inflammatory
  • Fever Reducer

Description

  • Indicated for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, juvenile arthritis, tendonitis, bursitis, acute gout, primary dysmenorrhea, and pain management
  • Blocks COX-1 and COX-2 enzymes to decrease prostaglandin synthesis
  • Dosage includes oral tablets, suspension, and gel for adults and children
  • Interacts with ACE inhibitors, antacids, aspirin, diuretics, methotrexate, warfarin, and selective serotonin reuptake inhibitors
  • Contraindicated in patients with hypersensitivity to Naproxen and perioperative pain in coronary artery bypass graft surgery
  • Side effects include gastrointestinal, central nervous system, dermatological, cardiovascular, visual, and hearing disturbances
  • May have adverse effects on fetus and excreted in small amounts in breast milk
  • Precautions for renal and hepatic effects, therapeutic class as NSAIDs for osteoarthritis and rheumatoid arthritis
  • Requires storage below 30°C, protected from light and moisture

Dimensions

N/A

Color Options

N/A

Functions

  • Relieves pain
  • Reduces fever
  • Manages inflammation
  • Delays parturition in animals

Materials

N/A

Technical Specifications

  • Adult dosage: 500-1000 mg per day in divided doses for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis
  • Children's suspension dosage based on weight
  • Gel to be applied 2-6 times a day as required

Design Elements

N/A

Usability Features

  • Oral preparations to be taken with water after meals
  • Dosage and administration instructions provided for various indications

Indications

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Juvenile arthritis
  • Tendonitis
  • Bursitis
  • Acute gout
  • Primary dysmenorrhea
  • Pain management

Pharmacology

Blocks COX-1 and COX-2 enzymes to decrease prostaglandin synthesis

Dosage & Administration

  • Oral preparations to be taken with water after meals
  • Dosage instructions for adults and children for various indications
  • Enteric-coated tablets and suspension available

Interaction

  • Diminishes antihypertensive effect of ACE inhibitors
  • Delays the absorption of Naproxen with antacids and sucralfate
  • Increases adverse effects when taken with aspirin
  • Reduces natriuretic effect of diuretics
  • Enhances the toxicity of Methotrexate
  • Increases the risk of GI bleeding with warfarin and selective serotonin reuptake inhibitors

Contraindications

  • Hypersensitivity to Naproxen
  • Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  • Treatment of perioperative pain in coronary artery bypass graft surgery

Side Effects

  • Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
  • Central Nervous System: Headache, vertigo, drowsiness
  • Dermatological: Pruritus (itching), purpura
  • Cardiovascular: Edema, palpitation
  • Others: Visual disturbances, hearing disturbances

Pregnancy & Lactation

  • Associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants born to mothers taking Naproxen
  • Excreted in small amounts in breast milk

Precautions & Warnings

  • Long-term administration may result in renal and hepatic effects
  • Caution in patients with significantly impaired renal function
  • Monitoring of serum creatinine and/or creatinine clearance advised
  • Few reports of moderate to severe jaundice attributed to Naproxen

Therapeutic Class

  • NSAIDs for osteoarthritis
  • NSAIDs for rheumatoid arthritis

Storage Conditions

Keep below 30°C temperature, protected from light & moisture, keep out of the reach of children

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