Naprosyn 125 mg/5 ml (Oral Suspension)
50 ml bottle: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Relief of rheumatoid arthritis
- Relief of osteoarthritis
- Relief of ankylosing spondylitis
- Relief of juvenile arthritis
- Relief of tendonitis
- Relief of bursitis
- Relief of acute gout
- Management of primary dysmenorrhea
Pharmacology
- Clinical effects by blocking COX-1 and COX-2 enzymes
- Decreased prostaglandin synthesis
- Unique functional differences of COX-1 and COX-2 enzymes
Dosage & Administration
- Oral administration with water
- Enteric Coated Tablet and Suspension formulations
- Different dosages for adults and children
- Dosage adjustment for juvenile rheumatoid arthritis
Interaction
- Diminished antihypertensive effect with ACE inhibitors
- Delayed absorption with Antacids & Sucralfate
- Increased adverse effects with Aspirin
- Reduced natriuretic effect with Diuretics
- Enhanced toxicity of Methotrexate
- Increased risk of GI bleeding with Warfarin and Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Treatment of perioperative pain in coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal effects like heartburn, abdominal pain, nausea, and diarrhea
- Central Nervous System effects like headache, vertigo, and drowsiness
- Dermatological effects like itching and purpura
- Cardiovascular effects like edema and palpitation
- Other effects like visual and hearing disturbances
Pregnancy & Lactation
- Adverse effects on the fetus
- Delay in parturition in animals
- Premature closure of the ductus arteriosus
- Severe pulmonary hypertension in infants
- Excretion in small amounts in breast milk
- Possible risks to the fetus
- Recommendation for careful balancing of benefits to the mother
Precautions & Warnings
- Renal effects including abnormal renal pathology in animals
- Reports of acute interstitial nephritis in humans
- Caution in patients with impaired renal function
- Monitoring of serum creatinine and/or creatinine clearance
- Caution for patients with significantly impaired renal function
- Reports of moderate to severe jaundice attributed to Naproxen
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children