Naproxin 500 mg (Tablet)
Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Ambee pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Ankylosing spondylitis
- Juvenile arthritis
- Tendonitis
- Bursitis
- Acute gout
- Primary dysmenorrhea & pain relief
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreased prostaglandin synthesis
- Unique functional differences between COX-1 and COX-2 enzymes
Dosage & Administration
- Should be taken with water after meals
- Different dosages for different indications
- Enteric Coated Tablets for adults and children
- Suspension for juvenile rheumatoid arthritis
- Gel for topical application
Interaction
- ACE inhibitors diminish antihypertensive effect
- Antacids & Sucralfate delay absorption
- Aspirin increases adverse effects
- Diuretics reduce natriuretic effect of Furosemide and Thiazides
- Methotrexate enhances toxicity
- Warfarin increases GI bleeding risk
- Selective Serotonin Reuptake Inhibitors increase GI bleeding risk
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Perioperative pain in the setting of CABG surgery
Side Effects
- Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System: Headache, vertigo, drowsiness
- Dermatological: Pruritus, purpura
- Cardiovascular: Edema, palpitation
- Others: Visual disturbances, hearing disturbances
Pregnancy & Lactation
- Adverse effect on fetus
- Causes delay in parturition in animals
- Associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants
- Excreted in small amounts in breast milk
Precautions & Warnings
- Renal effects: renal papillary necrosis, abnormal renal pathology, acute interstitial nephritis, hematuria, proteinuria, nephrotic syndrome
- Hepatic effects: moderate to severe jaundice
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children