Napsod 275 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Relief of rheumatoid arthritis
- Relief of osteoarthritis
- Relief of ankylosing spondylitis
- Relief of juvenile arthritis
- Relief of tendonitis
- Relief of bursitis
- Relief of acute gout
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreases prostaglandin synthesis
- Exerts antipyretic properties
- Exerts analgesic properties
- Exerts anti-inflammatory properties
- Linked to gastrointestinal upset
- Linked to renal toxicities
Dosage & Administration
- Taken with water
- Preferably after meals
- Adult dosage for various indications
- Children dosage for various indications
- Application frequency for gel
Interaction
- Diminishes antihypertensive effect of ACE inhibitors
- Delays the absorption of Napsod by antacids & Sucralfate
- Increases adverse effects with Aspirin
- Reduces the natriuretic effect of Diuretics
- Enhances the toxicity of Methotrexate
- Increases risk of GI bleeding with Warfarin and Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal side effects
- Central Nervous System side effects
- Dermatological side effects
- Cardiovascular side effects
- Other reported side effects
Pregnancy & Lactation
- Adverse effects on the fetus
- Causes delay in parturition in animals
- Associated with premature closure of the ductus arteriosus and severe pulmonary hypertension in infants
- Excreted in small amounts in breast milk
- Requires careful balancing of benefits to the mother against possible risks to the fetus
- Considered by some authorities to be too small to be harmful to a breast-fed infant
- Some manufacturers recommend avoiding breastfeeding during Naproxen therapy
Precautions & Warnings
- Renal effects
- Reports of abnormal renal pathology
- Acute interstitial nephritis
- Monitoring of serum creatinine and/or creatinine clearance advised
- Caution in patients with significantly impaired renal function
- Monitoring of hepatic function advised
- Reports of moderate to severe jaundice attributed to Napsod
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children