Nasox 500 mg (Tablet)
Unit Price: ৳ 3.88 (20's pack: ৳ 77.52)
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Seema pharmaceuticals ltd |
Indications
- Relief of rheumatoid arthritis symptoms
- Relief of osteoarthritis symptoms
- Relief of ankylosing spondylitis symptoms
- Relief of juvenile arthritis symptoms
- Relief of tendonitis symptoms
- Relief of bursitis symptoms
- Relief of acute gout symptoms
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreases prostaglandin synthesis
- Provides antipyretic, analgesic, and anti-inflammatory properties
Dosage & Administration
- Should be taken with water
- Preferably taken after meals
- Dosage varies for different conditions and age groups
- Oral tablets and suspension available
- Gel for external application
Interaction
- Diminishes antihypertensive effect of ACE inhibitors
- Delays the absorption of the product
- Increases adverse effects when taken with aspirin
- Reduces the natriuretic effect of diuretics
- Enhances the toxicity of Methotrexate
- Increases the risk of GI bleeding when taken with Warfarin and Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Known hypersensitivity to Naproxen
- Patients with asthma, urticaria, or allergic-type reactions to aspirin or other NSAIDs
- Patients undergoing coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal effects: heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System effects: headache, vertigo, drowsiness
- Dermatological effects: pruritus, purpura
- Cardiovascular effects: edema, palpitation
- Other effects: visual disturbances, hearing disturbances
Pregnancy & Lactation
- Adverse effects on fetus
- May cause delay in parturition
- Associated with premature closure of ductus arteriosus and severe pulmonary hypertension in infants
- Excreted in small amounts in breast milk
- Requires careful balancing of benefits and risks during pregnancy and lactation
Precautions & Warnings
- May result in renal papillary necrosis and abnormal renal pathology with long-term administration
- Reports of acute interstitial nephritis, hematuria, proteinuria, and nephrotic syndrome
- Eliminated primarily by the kidneys
- Use with caution in patients with impaired renal function
- Monitoring of serum creatinine and/or creatinine clearance advised
- Reports of moderate to severe jaundice
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children